ELO3 (SUR4/SRE1/APA1/VBM1, YLR372W; UniProt P40319) notes

Evidence journal (no paid deep research run; built from UniProt and cached publications).

Function

• ELO-family 3-keto-acyl-CoA synthase, EC 2.3.1.199 [UniProt:P40319]; forms elongase III PMID:12684876.
• PMID:9211877.
• PMID:9211877.
• sur4 membranes impaired beyond C22-CoA PMID:23325927.
• Molecular caliper: PMID:17719544.
• Elongase complex: PMID:12087109.

Location

• ER membrane PMID:11113186; PMID:9832547.

Curation decisions

• Post-Golgi transport (IMP, VBM1 suppressor) and MVB pathway (IGI with vps21) marked over-annotated: lipid-composition consequences.
• Cytosol RCA removed; PUFA IBA removed; MUFA IBA over-annotated; generic fatty acid biosynthetic process -> VLCFA biosynthesis.