GO_REF:0000002
Gene Ontology annotation through association of InterPro records with GO terms
GO_REF:0000033
Annotation inferences using phylogenetic trees
GO_REF:0000044
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
GO_REF:0000052
Gene Ontology annotation based on curation of immunofluorescence data
PMID:17460694
FANCI is a second monoubiquitinated member of the Fanconi anemia pathway.
PMID:18445686
EML3 is a nuclear microtubule-binding protein required for the correct alignment of chromosomes in metaphase.
PMID:18931676
FANCI phosphorylation functions as a molecular switch to turn on the Fanconi anemia pathway.
PMID:19946888
Defining the membrane proteome of NK cells.
PMID:19965384
The Fanconi anemia pathway promotes replication-dependent DNA interstrand cross-link repair.
PMID:19995904
DNA polymerase POLN participates in cross-link repair and homologous recombination.
PMID:19589784
FANCI binds branched DNA and is monoubiquitinated by UBE2T-FANCL.
PMID:22287633
DNA robustly stimulates FANCD2 monoubiquitylation in the complex with FANCI.
PMID:27694619
FANCI-FANCD2 stabilizes the RAD51-DNA complex by binding RAD51 and protects the 5'-DNA end.
PMID:20603015
Identification of KIAA1018/FAN1, a DNA repair nuclease recruited to DNA damage by monoubiquitinated FANCD2.
PMID:31240132
CTDP1 regulates breast cancer survival and DNA repair through BRCT-specific interactions with FANCI.
PMID:32269332
DNA clamp function of the monoubiquitinated Fanconi anaemia ID complex.
Reactome:R-HSA-6785342
FANCD2:FANCI complex and UBE2T bind ICL-DNA associated with the FA core complex
Reactome:R-HSA-6785361
Monoubiquitination of FANCD2:FANCI
Reactome:R-HSA-6785594
FANCD2 binds FANCI
Reactome:R-HSA-6785732
DNA nucleases bind monoubiquitinated ID2 complex
Reactome:R-HSA-6785986
DNA nucleases unhook the interstrand crosslink (ICL)
Reactome:R-HSA-6786155
POLN binds ICL-DNA
Reactome:R-HSA-6786166
Translesion synthesis across unhooked ICL by POLN
Reactome:R-HSA-6786171
FANCD2 deubiquitination by USP1:WDR48
Reactome:R-HSA-6788385
The complex of ATR and ATRIP is recruited to ICL-DNA
Reactome:R-HSA-6788392
ATR phosphorylates RPA2, FANCI, FANCD2 and FANCM at ICL-DNA
Reactome:R-HSA-6797712
CDK12 stimulates expression of DNA repair genes
PMID:17412408
Identification of the FANCI protein, a monoubiquitinated FANCD2 paralog required for DNA repair.
PMID:19465922
Replication stress induces sister-chromatid bridging at fragile site loci in mitosis.
PMID:19763158
Xpf and not the Fanconi anaemia proteins or Rev3 accounts for the extreme resistance to cisplatin in Dictyostelium discoideum.
PMID:30692263
Fanconi anemia protein FANCI functions in ribosome biogenesis.
PMID:30650351
Binding of FANCI-FANCD2 Complex to RNA and R-Loops Stimulates Robust FANCD2 Monoubiquitination.
PMID:25843623
ATR-mediated phosphorylation of FANCI regulates dormant origin firing in response to replication stress.
PMID:31219578
A Fanci knockout mouse model reveals common and distinct functions for FANCI and FANCD2.
PMID:34373449
FANCI plays an essential role in spermatogenesis and regulates meiotic histone methylation.
PMID:34256011
FANCI functions as a repair/apoptosis switch in response to DNA crosslinks.
PMID:26430909
FANCI Regulates Recruitment of the FA Core Complex at Sites of DNA Damage Independently of FANCD2.
file:human/FANCI/FANCI-deep-research-affinage.md
FANCI deep research (Affinage)
file:human/FANCI/FANCI-source-guide.md
FANCI — evidence and source guide