MCT1 (YOR221C, Q12283) notes

• Mitochondrial malonyl-CoA:ACP transacylase (FabD family, EC 2.3.1.39) of mtFAS [UniProt:Q12283 "Reaction=holo-[ACP] + malonyl-CoA = malonyl-[ACP] + CoA;"].
• Identified by homology; disruption -> respiratory deficiency PMID:9388293; PMID:9388293.
• Mitochondrial in proteomes (PMID:16823961, PMID:24769239).
• Uses malonyl-CoA produced in the matrix by HFA1 PMID:14761959.
• YeastPathways places MCT1 in cytosolic FAS pathways (PWY3O-10 etc.); in the cytosol malonyl transfer is done by the MPT domain of FAS1. Cytosol RCA rows wrong; MF correct.