Gene Ontology annotation through association of InterPro records with GO terms
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping
Deep research summary for ELF4
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ELF4 is a small structural subunit of the ELF3-ELF4-LUX Evening Complex, a nuclear transcriptional repressor complex central to Arabidopsis circadian timing.
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Recent Evening Complex literature supports EC-mediated repression of TOC1, LUX, GI, PRR7, PRR9, PIF4, and other clock or growth targets.
The ELF4 gene controls circadian rhythms and flowering time in Arabidopsis thaliana.
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ELF4 is involved in photoperiod perception and circadian regulation
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ELF4 promotes clock accuracy and is required for sustained rhythms
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elf4 mutants show attenuated CCA1 expression
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elf4 mutants flower early in non-inductive photoperiods due to elevated CO
EARLY FLOWERING 4 functions in phytochrome B-regulated seedling de-etiolation.
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ELF4 localizes to the nucleus
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elf4 mutants have reduced responsiveness to continuous red light
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ELF4 functions in phyB signaling but not phyA signaling
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ELF4 expression is induced by red light in a phyB-dependent manner
Functional profiling reveals that only a small number of phytochrome-regulated early-response genes in Arabidopsis are necessary for optimal deetiolation.
ELF4 is required for oscillatory properties of the circadian clock.
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ELF4 is necessary for entrainment to environmental cycles
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ELF4 is required for rhythm sustainability under constant conditions
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elf4 shows clock input defects in light responsiveness and circadian gating
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ELF4 is a component of the central CCA1/LHY-TOC1 feedback loop
Diversification of photoperiodic response patterns in a collection of early-flowering mutants of Arabidopsis.
Integrating ELF4 into the circadian system through combined structural and functional studies.
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ELF4 forms an alpha-helical homodimer
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Homodimer stability correlates with circadian function
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elf4 hypomorphic alleles affect both morning and evening clock genes
LUX ARRHYTHMO encodes a nighttime repressor of circadian gene expression in the Arabidopsis core clock.
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LUX directly regulates PRR9 expression
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LUX binds its own promoter in a negative autoregulatory loop
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The Evening Complex functions as a transcriptional repressor
The ELF4-ELF3-LUX complex links the circadian clock to diurnal control of hypocotyl growth.
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ELF4, ELF3, and LUX form the Evening Complex (EC)
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ELF3 bridges ELF4 and LUX interaction
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EC peaks at dusk and represses PIF4 and PIF5
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EC binds target promoters via LUX DNA-binding domain
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ChIP confirms ELF4 at PIF4/PIF5 promoters
EARLY FLOWERING4 recruitment of EARLY FLOWERING3 in the nucleus sustains the Arabidopsis circadian clock.