Gene Ontology annotation through association of InterPro records with GO terms

Annotation inferences using phylogenetic trees

Gene Ontology annotation based on curation of immunofluorescence data

Electronic Gene Ontology annotations created by ARBA machine learning models

Combined Automated Annotation using Multiple IEA Methods

Genetic heterogeneity in propionic acidemia patients with alpha-subunit defects. Identification of five novel mutations, one of them causing instability of the protein.

Mitochondrial targeting signals and mature peptides of 3-methylcrotonyl-CoA carboxylase.

N- and C-terminal domains in human holocarboxylase synthetase participate in substrate recognition.

Crystal structure of the alpha(6)beta(6) holoenzyme of propionyl-coenzyme A carboxylase.

Propionyl-CoA carboxylase - A review.

A reference map of the human binary protein interactome.

Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.

Isolation of cDNA clones coding for the alpha and beta chains of human propionyl-CoA carboxylase: chromosomal assignments and DNA polymorphisms associated with PCCA and PCCB genes.

Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context.

Multimodal cell maps as a foundation for structural and functional genomics.

Isolation and characterization of propionyl-CoA carboxylase from normal human liver. Evidence for a protomeric tetramer of nonidentical subunits.

Cloning of functional alpha propionyl CoA carboxylase and correction of enzyme deficiency in pccA fibroblasts.

HLCS biotinylates 6x(PCCA:PCCB)

An unknown protease degrades hCBXs

Cytosolic carboxylases translocate to mitochondrial matrix

propionyl-CoA + CO2 + ATP <=> D-methylmalonyl-CoA + ADP + orthophosphate

Defective HLCS does not biotinylate 6x(PCCA:PCCB)