LYS4 (YDR234W, P49367) notes

Pathway context: LYSINE-AMINOAD-PWY-2, homoaconitase (EC 4.2.1.36).

• Key finding: Lys4 only interconverts cis-homoaconitate and homoisocitrate; homocitrate -> cis-homoaconitate is done by Aco2 PMID:23106124; PMID:23106124. GO:0004409 is defined as the homoisocitrate = cis-homoaconitate + H2O reaction, so it fits Lys4 exactly. Module should include ACO2 for the homocitrate dehydratase half-reaction.
• Homology to A. nidulans LysF and Fe-S cysteines PMID:9268014.
• Genetics: PMID:2507177.
• Location: mitochondrion [UniProt:P49367; PMID:14562095]. RCA cytosol MODIFY -> mitochondrion. Rsp5 WW-array protein binding REMOVE.