Gene Ontology annotation through association of InterPro records with GO terms
Gene Ontology annotation by the MGI curatorial staff, curated orthology
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Automatic assignment of GO terms using logical inference, based on on inter-ontology links
Electronic Gene Ontology annotations created by ARBA machine learning models
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Combined Automated Annotation using Multiple IEA Methods
Localization of the murine Niemann-Pick C1 protein to two distinct intracellular compartments.
Disruption of ClC-3, a chloride channel expressed on synaptic vesicles, leads to a loss of the hippocampus.
Rab27a regulates the peripheral distribution of melanosomes in melanocytes.
Intact lysosome transport and phagosome function despite kinectin deficiency.
Dynamics of major histocompatibility complex class II compartments during B cell receptor-mediated cell activation.
Small GTPase Rah/Rab34 is associated with membrane ruffles and macropinosomes and promotes macropinosome formation.
Impaired membrane resealing and autoimmune myositis in synaptotagmin VII-deficient mice.
Dysferlin interacts with annexins A1 and A2 and mediates sarcolemmal wound-healing.
Emerging role for autophagy in the removal of aggresomes in Schwann cells.
Accelerated antigen presentation and elicitation of humoral response in vivo by FcgammaRIIB- and FcgammaRI/III-mediated immune complex uptake.
Mammalian late vacuole protein sorting orthologues participate in early endosomal fusion and interact with the cytoskeleton.
Sialin expression in the CNS implicates extralysosomal function in neurons.
AP-3-dependent mechanisms control the targeting of a chloride channel (ClC-3) in neuronal and non-neuronal cells.
Alfy, a novel FYVE-domain-containing protein associated with protein granules and autophagic membranes.
Endoplasmic reticulum-associated degradation-induced dissociation of class II invariant chain complexes containing a glycosylation-deficient form of p41.
Membrane trafficking and mitochondrial abnormalities precede subunit c deposition in a cerebellar cell model of juvenile neuronal ceroid lipofuscinosis.
Distribution and dynamics of Lamp1-containing endocytic organelles in fibroblasts deficient in BLOC-3.
The Unc93b1 mutation 3d disrupts exogenous antigen presentation and signaling via Toll-like receptors 3, 7 and 9.
Palmitoyl protein thioesterase 1 (PPT1) deficiency causes endocytic defects connected to abnormal saposin processing.
Amelogenin, a major structural protein in mineralizing enamel, is also expressed in soft tissues: brain and cells of the hematopoietic system.
BLOC-1 complex deficiency alters the targeting of adaptor protein complex-3 cargoes.
Cellular mechanisms of fatal early-onset autoimmunity in mice with the T cell-specific targeting of transforming growth factor-beta receptor.
Lysosomal accumulation of SCMAS (subunit c of mitochondrial ATP synthase) in neurons of the mouse model of mucopolysaccharidosis III B.
Slc11a1, formerly Nramp1, is expressed in dendritic cells and influences major histocompatibility complex class II expression and antigen-presenting cell function.
Glypican-3 inhibits Hedgehog signaling during development by competing with patched for Hedgehog binding.
Comparative analysis of testis protein evolution in rodents.
Impaired NK cytolytic activity and enhanced tumor growth in NK lytic-associated molecule-deficient mice.
The lysosomal polypeptide transporter TAPL: more than a housekeeping factor?
Raftlin is involved in the nucleocapture complex to induce poly(I:C)-mediated TLR3 activation.
Salmonella acquires lysosome-associated membrane protein 1 (LAMP1) on phagosomes from Golgi via SipC protein-mediated recruitment of host Syntaxin6.
The lysosomal polypeptide transporter TAPL is stabilized by interaction with LAMP-1 and LAMP-2.
The E3-ubiquitin ligase TRIM50 interacts with HDAC6 and p62, and promotes the sequestration and clearance of ubiquitinated proteins into the aggresome.
Role for phospholipid flippase complex of ATP8A1 and CDC50A proteins in cell migration.
HRG1 is essential for heme transport from the phagolysosome of macrophages during erythrophagocytosis.
The giant spectrin βV couples the molecular motors to phototransduction and Usher syndrome type I proteins along their trafficking route.
Surface CD107a/LAMP-1 protects natural killer cells from degranulation-associated damage.
Goofy coordinates the acuity of olfactory signaling.
Haploinsufficiency of SAMD9L, an endosome fusion facilitator, causes myeloid malignancies in mice mimicking human diseases with monosomy 7.
Christianson syndrome protein NHE6 modulates TrkB endosomal signaling required for neuronal circuit development.
The late endosomal p14-MP1 (LAMTOR2/3) complex regulates focal adhesion dynamics during cell migration.
In Vivo Evidence for Lysosome Depletion and Impaired Autophagic Clearance in Hereditary Spastic Paraplegia Type SPG11.
Novel Role of TRPML2 in the Regulation of the Innate Immune Response.
CCC- and WASH-mediated endosomal sorting of LDLR is required for normal clearance of circulating LDL.
Intrinsically Disordered Protein TEX264 Mediates ER-phagy.
Loss of spatacsin impairs cholesterol trafficking and calcium homeostasis.
The NK cell granule protein NKG7 regulates cytotoxic granule exocytosis and inflammation.
Lysosomal LAMP proteins regulate lysosomal pH by direct inhibition of the TMEM175 channel.
Normal lysosomal morphology and function in LAMP-1-deficient mice.
Disturbed cholesterol traffic but normal proteolytic function in LAMP-1/LAMP-2 double-deficient fibroblasts.
Lysosome-associated membrane proteins-1 and -2 (LAMP-1 and LAMP-2) assemble via distinct modes.
LAMP1/CD107a is required for efficient perforin delivery to lytic granules and NK-cell cytotoxicity.
A novel role for α-tocopherol transfer protein (α-TTP) in protecting against chloroquine toxicity.
Combined apoptosis and autophagy, the process that eliminates the oocytes of atretic follicles in immature rats.
Molecular characterization of P2B/LAMP-1, a major protein target of a metastasis-associated oligosaccharide structure.
UniProt entry P11438 (LAMP1_MOUSE)
Manual literature synthesis for mouse Lamp1