Annotation inferences using phylogenetic trees

Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt

Gene Ontology annotation based on curation of immunofluorescence data

Combined Automated Annotation using Multiple IEA Methods

UniProtKB entry DOLK_HUMAN (Q9UPQ8)

Expression and characterization of a human cDNA that complements the temperature-sensitive defect in dolichol kinase activity in the yeast sec59-1 mutant: the enzymatic phosphorylation of dolichol and diacylglycerol are catalyzed by separate CTP-mediated kinase activities in Saccharomyces cerevisiae.

Human dolichol kinase, a polytopic endoplasmic reticulum membrane protein with a cytoplasmically oriented CTP-binding site.

A defect in dolichol phosphate biosynthesis causes a new inherited disorder with death in early infancy.

Autosomal recessive dilated cardiomyopathy due to DOLK mutations results from abnormal dystroglycan O-mannosylation.

A proteome-scale map of the human interactome network.

Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.

Architecture of the human interactome defines protein communities and disease networks.

A reference map of the human binary protein interactome.

Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.

DOLK phosphorylates DCHOL to DOLP

Synthesis of dolichyl-phosphate

Defective DOLK does not phosphorylate DCHOL