Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Annotation inferences using phylogenetic trees
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Combined Automated Annotation using Multiple IEA Methods
TULP3 bridges the IFT-A complex and membrane phosphoinositides to promote trafficking of G protein-coupled receptors into primary cilia.
Human and mouse mutations in WDR35 cause short-rib polydactyly syndromes due to abnormal ciliogenesis.
An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.
Role for the IFT-A Complex in Selective Transport to the Primary Cilium.
Intraflagellar transport-A complex mediates ciliary entry and retrograde trafficking of ciliary G protein-coupled receptors.
Ciliopathy-associated mutations of IFT122 impair ciliary protein trafficking but not ciliogenesis.
Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.
Human IFT-A complex structures provide molecular insights into ciliary transport.
Multimodal cell maps as a foundation for structural and functional genomics.
GPR45 modulates Gα(s) at primary cilia of the paraventricular hypothalamus to control food intake.
TULP3 is required for GPR161 localization in the cilium
The IFT-A complex recruits TULP3
Assembly of IFT A complex
Assembly of the anterograde IFT train
Assembly of the retrograde IFT train
The anterograde IFT train dissociates
The retrograde IFT train dissociates
Falcon deep research report for WDR35 (human)
UniProt entry Q9P2L0 (WDR35_HUMAN)