Gene Ontology annotation through association of InterPro records with GO terms

Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity

Annotation inferences using phylogenetic trees

Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt

Gene Ontology annotation based on curation of immunofluorescence data

Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara

Automatic assignment of GO terms using logical inference, based on on inter-ontology links

Electronic Gene Ontology annotations created by ARBA machine learning models

Combined Automated Annotation using Multiple IEA Methods

EHD2, EHD3, and EHD4 encode novel members of a highly conserved family of EH domain-containing proteins.

Rabenosyn-5 and EHD1 interact and sequentially regulate protein recycling to the plasma membrane.

Shared as well as distinct roles of EHD proteins revealed by biochemical and functional comparisons in mammalian cells and C. elegans.

EHD3 regulates early-endosome-to-Golgi transport and preserves Golgi morphology.

MICAL-L1 links EHD1 to tubular recycling endosomes and regulates receptor recycling.

EH domain proteins regulate cardiac membrane protein targeting.

Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation.

Endocytosis promotes rapid dopaminergic signaling.

Early steps in primary cilium assembly require EHD1/EHD3-dependent ciliary vesicle formation.

SUMOylation of EHD3 Modulates Tubulation of the Endocytic Recycling Compartment.

EHD3 Protein Is Required for Tubular Recycling Endosome Stabilization, and an Asparagine-Glutamic Acid Residue Pair within Its Eps15 Homology (EH) Domain Dictates Its Selective Binding to NPF Peptides.

Architecture of the human interactome defines protein communities and disease networks.

A reference map of the human binary protein interactome.

Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.

EHD proteins interact with Rabenosyn-5

EHD3: a protein that resides in recycling tubular and vesicular membrane structures and interacts with EHD1.

ATP binding regulates oligomerization and endosome association of RME-1 family proteins.

Deep research report (EHD3-deep-research-falcon.md)