Gene Ontology annotation through association of InterPro records with GO terms
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Annotation inferences using phylogenetic trees
Combined Automated Annotation using Multiple IEA Methods
Drosophila glucome screening identifies Ck1alpha as a regulator of mammalian glucose metabolism.
UniProtKB E1JIZ4 (Men-b, Drosophila melanogaster) TrEMBL record
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Rule-based malic enzyme assignment, Mg2+/Mn2+ cofactor, homotetramer.
"RecName: Full=Malic enzyme"
IDH2-mediated regulation of the biogenesis of the oxidative phosphorylation system.
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Men-b (dME3, CG5889) is the fly ME3 ortholog; flight-muscle RNAi of dME3 impairs complex I assembly and causes early adult lethality.
"We conclude that disruption of dME3 impairs the biogenesis or stability of the Q- and N-modules to trigger a disruption in CI assembly."