Spcs2: exact selected product and same-gene reference

Selected A0A140LHW5 has 74 residues; reference Q9CYN2 has 226 residues.

Biopython PairwiseAligner global BLOSUM62, gap open -10, extension -0.5.

Reference interval Selected interval Identical residues
1–66 1–66 66
110–112 67–69 1
144–147 70–73 2
226–226 74–74 0

Reference feature mapping (sequence coverage does not establish retained function):

Reference feature Interval Mapped / length Identical
Transmembrane: Helical 87–107 0 / 21 0
Transmembrane: Helical 112–132 1 / 21 1

A shared segment does not establish that a truncated product folds, is expressed, localizes, or catalyzes the full-length reaction.

Inputs are the sibling frozen ProtNLM source and same-gene reference JSON files. Reproduce with UV_NO_SYNC=1 uv run python compare_sequences.py from this directory.