Gene Ontology annotation through association of InterPro records with GO terms

Annotation inferences using phylogenetic trees

Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt

Gene Ontology annotation based on curation of immunofluorescence data

Combined Automated Annotation using Multiple IEA Methods

The COP9 complex, a novel multisubunit nuclear regulator involved in light control of a plant developmental switch.

A novel protein complex involved in signal transduction possessing similarities to 26S proteasome subunits.

Hepatopoietin interacts directly with COP9 signalosome and regulates AP-1 activity.

Characterization of the human COP9 signalosome complex using affinity purification and mass spectrometry.

Large-scale proteomics and phosphoproteomics of urinary exosomes.

Symmetrical modularity of the COP9 signalosome complex suggests its multifunctionality.

Defining the human deubiquitinating enzyme interaction landscape.

Structural insights into the COP9 signalosome and its common architecture with the 26S proteasome lid and eIF3.

Dynamics of cullin-RING ubiquitin ligase network revealed by systematic quantitative proteomics.

microRNA-146a inhibits G protein-coupled receptor-mediated activation of NF-κB by targeting CARD10 and COPS8 in gastric cancer.

COP9 signalosome subunit Csn8 is involved in maintaining proper duration of the G1 phase.

Dynamic regulation of the COP9 signalosome in response to DNA damage.

Human-chromatin-related protein interactions identify a demethylase complex required for chromosome segregation.

Crystal structure of the human COP9 signalosome.

A proteome-scale map of the human interactome network.

A human interactome in three quantitative dimensions organized by stoichiometries and abundances.

Cullin-RING ubiquitin E3 ligase regulation by the COP9 signalosome.

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

Architecture of the human interactome defines protein communities and disease networks.

A reference map of the human binary protein interactome.

Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.

Multimodal cell maps as a foundation for structural and functional genomics.

XPC:RAD23:CETN2 and UV-DDB bind distorted dsDNA site

ERCC8 (CSA) binds stalled RNA Pol II

NEDD8-STON binds TOR1 hexamer and COP9 complex

COP9 and TOR1 deneddylate STON2

COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes

COP9 signalosome deneddylates nuclear CRL4 E3 ubiquitin ligase complex

Deep research synthesis on COPS8/CSN8 function