Falcon deep research report for XIST
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Falcon supports XIST as a noncoding RNA chromatin scaffold/adaptor that coats the inactive X in cis, recruits silencing and chromatin-modifying factors, and establishes repressive chromatin during X-chromosome inactivation.
"XIST's core molecular role is an RNA/chromatin scaffold or adaptor that coats the inactive X in cis, recruits transcriptional repressors and chromatin-modifying complexes, and helps establish repressive chromatin."
Recent advances in X-chromosome inactivation research
Xist has properties of the X-chromosome inactivation centre
X chromosome inactivation in human development
The Molecular and Nuclear Dynamics of X-Chromosome Inactivation
Automatic Gene Ontology annotation of non-coding RNA sequences through association of Rfam records with GO terms
Systematic discovery of Xist RNA binding proteins.
XIST promotes gastric cancer (GC) progression through TGF-β1 via targeting miR-185.
Cellular functions of long noncoding RNAs.
Progress toward understanding chromosome silencing by Xist RNA.
Structural modularity of the XIST ribonucleoprotein complex.
Stabilization of Xist RNA mediates initiation of X chromosome inactivation.