The review contains 61 original contexts, one fission core and two natural products. Its 87 reference assessments distinguish actual source access from inference. There are no NEW annotations. The external evidence page centralizes experimental constructs and dataset locators; source evidence and the compact archive preserve machine provenance.
All 41 binding contexts retain positive source pairs. Seventeen receive supported partner-class refinements; 24 retain the evidence while removing generic protein binding. This does not transfer the partner's activity to GDAP1. Literal HuRI products and the gene-level Haenig table remain distinct.
The actual PANTHER tree/alignment places the exact human sequence beneath the three IBD assertions. Human self-donation is valid experimental grounding. The fusion judgment concerns the interpretation of pathogenic-variant evidence, not donor count, topology or circularity.
The genuine native seed omits raw47's sperm atom. The review restores that single BFO:0000050 context while preserving all original fields and forecast ordering. No old review or historical quotation associations existed in the qualified namespace. The archive includes both natural sequences and lossless raw rows; later raw regeneration cannot replace these dated original identifiers.
Selected original sections were inspected for the dynamics, peroxisomal and biochemical sources named on the external page. Target dataset rows were independently inspected for the two interaction screens and MitoCoP. Disease/sequence background assessments are abstract-bounded; no title alone establishes catalysis or an assay on GDAP1. Full text remains unavailable where stated. Official HPA metadata is not independent image inspection.
Genuine target refresh and native seeding reproduced all 61 original contexts and 61 seed keys. All 37 normal sources are present: 14 reused unchanged and 23 acquired only because they were missing, including two family files. Native titles and all four excerpts are reconciled; two excerpts required only linebreak adaptation. Selected full text for PMID22206013 and the complete Reactome9603798 model summary were read. Reviewer access remains distinct from cache extraction scope. Default validation, strict matching of all 61 original GOA contexts, computed-status audit, history validation, scoped whitespace and private rendering passed. Computed status is COMPLETE with zero annotation advisories. The sperm-nucleus context remains UNDECIDED with its literal cell extension. All 37 source bytes and the ontology cache remain unchanged after acquisition.
The 61 original contexts now comprise 10 ACCEPT, 20 MODIFY, 24 REMOVE, three KEEP_AS_NON_CORE, three MARK_AS_OVER_ANNOTATED and one UNDECIDED. Three broad location terms are refined through checked is_a/part_of paths; all 17 measured partner-class binding refinements remain, with individual native-access caveats. TAGLN2 and BOK use selected primary evidence rather than partner GO lines. Seventeen compact excerpts are locally checkable on the external evidence page. The single mitochondrial-fission core is restricted to the mitochondrial outer membrane; peroxisomal evidence remains elsewhere. A biological knowledge gap records unresolved native chemistry. No NEW annotation or machine-context change is proposed.
The actual ancestry analysis used PANTHER19.0's PTHR44188 tree, alignment, MIA and attributes. The retained normal family files and lossless archive remain part of the source closure; they are not removed because no annotation quote points to them.
The initial validation results above describe published head 0aff94c. The follow-up is now applied with 39 normal sources: all 37 published sources remain exact, PMID26949185 was hydrated from its unchanged existing Git blob, and only PMID25869671 was newly fetched. Both titles match the proposal; the latter cache is full XML while the BOK cache remains abstract-only despite selected original full-text access. The archive, products, original excerpts and journal prefix are preserved. Default validation, strict matching of all 61 original GOA contexts, computed-status audit, genuine EDIT history validation, private rendering and scoped whitespace passed. Computed status is COMPLETE with zero annotation advisories. All 37 prior source bytes, the original archive, both products and the ontology cache remain unchanged; the 39-source closure includes one genuine new publication and one exact existing-object hydration.
All 17 partner-class excerpts now retain their actual evidence basis. Twelve UniProt fields have experimental attribution, one has curator-inferred family membership, and two have curated text without a per-field ECO array. Two excerpts come from independently inspected original papers and have no UniProt ECO field. Mixed paragraphs retain their complete arrays and the selected claim's narrower citation scope. Accession-relative pointers accompany the preserved response pointers and hashes. No partner's activity is transferred to GDAP1.
The peroxisomal-role discussion separates positive biology from the provenance decision for a new human annotation. All 61 existing actions, original machine fields, two products, one core, 87 reference records and 21 excerpts are preserved. The 39 scientific sources and original archive remain unchanged. Default validation, strict matching of all 61 original GOA contexts, computed-status audit, genuine EDIT history validation, private rendering and scoped whitespace passed. Computed status is COMPLETE with zero annotation advisories. All 39 scientific sources, the original archive, both products, all 21 excerpt texts and the ontology cache are unchanged. Earlier validation results above describe their respective historical states.