Gene Ontology annotation through association of InterPro records with GO terms
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Automatic assignment of GO terms using logical inference, based on on inter-ontology links
Electronic Gene Ontology annotations created by ARBA machine learning models
Combined Automated Annotation using Multiple IEA Methods
OpenScientist GO-focused literature synthesis for yeast HST1
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The report identifies recruitment-partner specificity as a key distinction between Hst1 and Sir2.
"specificity is set by non-conserved N-terminal sequences and a small number of core residues, not by catalysis."
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The report distinguishes locus-specific H4K5 evidence from family-level H3/H4 lysine observations.
"For Hst1 specifically, in vivo evidence comes from the observation"
HST1, a new member of the SIR2 family of genes.
Sum1 and Hst1 repress middle sporulation-specific gene expression during mitosis in Saccharomyces cerevisiae.
NAD+-dependent deacetylase Hst1p controls biosynthesis and cellular NAD+ levels in Saccharomyces cerevisiae.
Swapping the gene-specific and regional silencing specificities of the Hst1 and Sir2 histone deacetylases.
Repression of Middle Sporulation Genes in Saccharomyces cerevisiae by the Sum1-Rfm1-Hst1 Complex Is Maintained by Set1 and H3K4 Methylation.
A novel form of transcriptional silencing by Sum1-1 requires Hst1 and the origin recognition complex.
The S. cerevisiae SET3 complex includes two histone deacetylases, Hos2 and Hst1, and is a meiotic-specific repressor of the sporulation gene program.
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Hst1-containing complexes deacetylate several histone substrates; dispensability for the tested Set3C meiotic phenotype does not establish absence of all Hst1 function.
"the activities associated with Set3C and Hst1–Sum1 complex deacetylate several histone substrates in vitro with no apparent substrate specificity"
Rfm1, a novel tethering factor required to recruit the Hst1 histone deacetylase for repression of middle sporulation genes.
HST2 mediates SIR2-independent life-span extension by calorie restriction.
Proteome survey reveals modularity of the yeast cell machinery.
Control of replication initiation by the Sum1/Rfm1/Hst1 histone deacetylase.
Thiamine biosynthesis in Saccharomyces cerevisiae is regulated by the NAD+-dependent histone deacetylase Hst1.
Determinants of Sir2-Mediated, Silent Chromatin Cohesion.
The cellular economy of the Saccharomyces cerevisiae zinc proteome.
The social and structural architecture of the yeast protein interactome.
PubMed figure-caption evidence for Hst1 in PMID:27185881