Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Gene Ontology annotation based on curation of immunofluorescence data
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Electronic Gene Ontology annotations created by ARBA machine learning models
Combined Automated Annotation using Multiple IEA Methods
Comprehensive proteomic analysis of interphase and mitotic 14-3-3-binding proteins.
Targeted proteomic analysis of 14-3-3 sigma, a p53 effector commonly silenced in cancer.
The ubiquitin isopeptidase UBPY regulates endosomal ubiquitin dynamics and is essential for receptor down-regulation.
The MIT domain of UBPY constitutes a CHMP binding and endosomal localization signal required for efficient epidermal growth factor receptor degradation.
Final stages of cytokinesis and midbody ring formation are controlled by BRUCE.
Dynamic regulation of ubiquitylation and deubiquitylation at the central spindle during cytokinesis.
Usp39 is essential for mitotic spindle checkpoint integrity and controls mRNA-levels of aurora B.
Ab initio protein modelling reveals novel human MIT domains.
Interactions with LC3 and polyubiquitin chains link nbr1 to autophagic protein turnover.
Balanced ubiquitylation and deubiquitylation of Frizzled regulate cellular responsiveness to Wg/Wnt.
HIF1α deubiquitination by USP8 is essential for ciliogenesis in normoxia.
E-cadherin interactome complexity and robustness resolved by quantitative proteomics.
The Endosome-associated Deubiquitinating Enzyme USP8 Regulates BACE1 Enzyme Ubiquitination and Degradation.
Deubiquitinase Usp8 regulates α-synuclein clearance and modifies its toxicity in Lewy body disease.
Somatic USP8 Gene Mutations Are a Common Cause of Pediatric Cushing Disease.
Architecture of the human interactome defines protein communities and disease networks.
Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.
OpenCell: Endogenous tagging for the cartography of human cellular organization.
A central chaperone-like role for 14-3-3 proteins in human cells.
UBPY: a growth-regulated human ubiquitin isopeptidase.
Deubiquitinating enzymes: a new class of biological regulators.
Phosphorylation of USP8 by P-AKT
Deubiquitination of RNF41 by P-USP8
Ubiquitinated RNF41 binds P-USP8
USP8 deubiquitinates FZD to potentiate WNT signaling
USP8 deubiquitinates RNF128
USP8 deubiquitinates STAM2:HGS
USP8 deubiquitinates LRIG1