GO_REF:0000024
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity.
GO_REF:0000033
Annotation inferences using phylogenetic trees
GO_REF:0000043
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
GO_REF:0000044
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt.
GO_REF:0000120
Combined Automated Annotation using Multiple IEA Methods.
PMID:12671034
Purification, localization, and expression of human intestinal alkaline sphingomyelinase.
PMID:12885774
Identification of human intestinal alkaline sphingomyelinase as a novel ecto-enzyme related to the nucleotide phosphodiesterase family.
PMID:15205117
Pancreatic trypsin cleaves intestinal alkaline sphingomyelinase from mucosa and enhances the sphingomyelinase activity.
PMID:16255717
Intestinal alkaline sphingomyelinase hydrolyses and inactivates platelet-activating factor by a phospholipase C activity.
PMID:28292932
Crystal structure of the human alkaline sphingomyelinase provides insights into substrate recognition.
PMID:32296183
A reference map of the human binary protein interactome.
Reactome:R-HSA-1640164
ENPP7 hydrolyzes sphingomyelin
Reactome:R-HSA-9840310
Glycosphingolipid catabolism
file:human/ENPP7/ENPP7-deep-research-perplexity-lite.md
Deep research on ENPP7 function
file:human/ENPP7/ENPP7-deep-research-falcon.md
Falcon (Edison) deep research report on ENPP7 function, structure, and disease associations
PMID:34958798
Structure and function of the ecto-nucleotide pyrophosphatase/phosphodiesterase (ENPP) family - Tidying up diversity.
PMID:37137910
Identification of biomarkers for glycaemic deterioration in type 2 diabetes.
PMID:39728440
Structural and Functional Integration of Tissue-Nonspecific Alkaline Phosphatase Within the Alkaline Phosphatase Superfamily: Evolutionary Insights and Functional Implications.
PMID:39698091
Evolutionary conservation analysis of human sphingomyelin metabolism pathway genes.