GO_REF:0000033
Annotation inferences using phylogenetic trees
PMID:19468067
Mitotic control of kinetochore-associated dynein and spindle orientation by human Spindly.
PMID:17600710
Cenp-F links kinetochores to Ndel1/Nde1/Lis1/dynein microtubule motor complexes.
GO_REF:0000107
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
PMID:16547491
p78/MCRS1 forms a complex with centrosomal protein Nde1 and is essential for cell viability.
PMID:16682949
Centrosomal proteins Nde1 and Su48 form a complex regulated by phosphorylation.
PMID:22843697
The mitosis and neurodevelopment proteins NDE1 and NDEL1 form dimers, tetramers, and polymers with a folded back structure in solution.
PMID:25332407
Identification of Rare, Single-Nucleotide Mutations in NDE1 and Their Contributions to Schizophrenia Susceptibility.
PMID:29961565
Endogenous Cell Type-Specific Disrupted in Schizophrenia 1 Interactomes Reveal Protein Networks Associated With Neurodevelopmental Disorders.
PMID:31413325
HENA, heterogeneous network-based data set for Alzheimer's disease.
PMID:33961781
Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.
PMID:35271311
OpenCell: Endogenous tagging for the cartography of human cellular organization.
PMID:40205054
Multimodal cell maps as a foundation for structural and functional genomics.
PMID:21399614
Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods.
PMID:21529752
The essential role of centrosomal NDE1 in human cerebral cortex neurogenesis.
GO_REF:0000120
Combined Automated Annotation using Multiple IEA Methods
Reactome:R-HSA-141409
Mad1 binds kinetochore
Reactome:R-HSA-141422
MAD2 converted to an inhibitory state via interaction with Mad1
Reactome:R-HSA-141431
MAD2 associates with the Mad1 kinetochore complex
Reactome:R-HSA-141439
Release of activated MAD2 from kinetochores
Reactome:R-HSA-1638803
Phosphorylation of cohesin by PLK1 at centromeres
Reactome:R-HSA-1638821
PP2A-B56 dephosphorylates centromeric cohesin
Reactome:R-HSA-2467809
ESPL1 (Separase) cleaves centromeric cohesin
Reactome:R-HSA-2467811
Separation of sister chromatids
Reactome:R-HSA-2468287
CDK1 phosphorylates CDCA5 (Sororin) at centromeres
Reactome:R-HSA-2484822
Kinetochore assembly
Reactome:R-HSA-2574840
AJUBA facilitates AURKA autophosphorylation
Reactome:R-HSA-2574845
AJUBA binds centrosome-associated AURKA
Reactome:R-HSA-3000310
AURKA phosphorylates PLK1
Reactome:R-HSA-3000319
BORA binds PLK1 and AURKA
Reactome:R-HSA-375302
Kinetochore capture of astral microtubules
Reactome:R-HSA-380272
Plk1-mediated phosphorylation of Nlp
Reactome:R-HSA-380283
Recruitment of additional gamma tubulin/ gamma TuRC to the centrosome
Reactome:R-HSA-380294
Loss of C-Nap-1 from centrosomes
Reactome:R-HSA-380303
Dissociation of Phospho-Nlp from the centrosome
Reactome:R-HSA-380311
Recruitment of Plk1 to centrosomes
Reactome:R-HSA-380316
Association of NuMA with microtubules
Reactome:R-HSA-380455
Recruitment of CDK11p58 to the centrosomes
Reactome:R-HSA-380508
Translocation of NuMA to the centrosomes
Reactome:R-HSA-5617816
RAB3IP stimulates nucleotide exchange on RAB8A
Reactome:R-HSA-5626220
C2CD3 binds the mother centriole
Reactome:R-HSA-5626223
C2CD3 and OFD1 recruit 5 distal appendage proteins to the centriole
Reactome:R-HSA-5626227
CP110 and CEP97 dissociate from the centriole
Reactome:R-HSA-5626228
The distal appendage proteins recruit TTBK2
Reactome:R-HSA-5626681
Recruitment of transition zone proteins
Reactome:R-HSA-5626699
MARK4 binds ODF2 in the centriole
Reactome:R-HSA-5638009
CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body
Reactome:R-HSA-5666129
CDC42:GTP recruits DIAPH2-2 to kinetochores
Reactome:R-HSA-5666160
AURKB phosphorylates DIAPH2-2 at kinetochores
Reactome:R-HSA-5666169
Kinetochore capture of astral microtubules is positively regulated by CDC42:GTP:p-S196-DIAPH2-2
Reactome:R-HSA-8853405
TPX2 binds AURKA at centrosomes
Reactome:R-HSA-8853419
TPX2 promotes AURKA autophosphorylation
Reactome:R-HSA-9648114
EML4 recruits NUDC to mitotic spindle
GO_REF:0000044
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
GO_REF:0000024
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
PMID:19946888
Defining the membrane proteome of NK cells.
PMID:34793709
Nde1 is a Rab9 effector for loading late endosomes to cytoplasmic dynein motor complex.
PMID:17682047
NudE and NudEL are required for mitotic progression and are involved in dynein recruitment to kinetochores.
PMID:27553190
Severe NDE1-mediated microcephaly results from neural progenitor cell cycle arrests at multiple specific stages.
PMID:21383080
A Nup133-dependent NPC-anchored network tethers centrosomes to the nuclear envelope in prophase.
PMID:25245017
The scaffold protein Nde1 safeguards the brain genome during S phase of early neural progenitor differentiation.
PMID:21394081
Nde1-mediated inhibition of ciliogenesis affects cell cycle re-entry.
PMID:35493069
Nde1 and Ndel1: Outstanding Mysteries in Dynein-Mediated Transport.
PMID:15473967
Mitotic spindle regulation by Nde1 controls cerebral cortical size.
PMID:21529751
Human mutations in NDE1 cause extreme microcephaly with lissencephaly [corrected].
PMID:37940657
Nde1 promotes Lis1-mediated activation of dynein.
PMID:20403325
LIS1 and NudE induce a persistent dynein force-producing state.
PMID:39167527
The Role of Nde1 phosphorylation in interkinetic nuclear migration and neural migration during cortical development.