Gene Ontology annotation through association of InterPro records with GO terms
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Gene Ontology annotation based on curation of immunofluorescence data
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Malignant lymphoma and rheumatic symptoms.
Tollip, a new component of the IL-1RI pathway, links IRAK to the IL-1 receptor.
IRAK1b, a novel alternative splice variant of interleukin-1 receptor-associated kinase (IRAK), mediates interleukin-1 signaling and has prolonged stability.
Cooperation of Toll-like receptor 2 and 6 for cellular activation by soluble tuberculosis factor and Borrelia burgdorferi outer surface protein A lipoprotein: role of Toll-interacting protein and IL-1 receptor signaling molecules in Toll-like receptor 2 signaling.
Tom1, a VHS domain-containing protein, interacts with tollip, ubiquitin, and clathrin.
Tollip and Tom1 form a complex and recruit ubiquitin-conjugated proteins onto early endosomes.
Towards a proteome-scale map of the human protein-protein interaction network.
Recruitment of clathrin onto endosomes by the Tom1-Tollip complex.
A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.
Large-scale proteomics and phosphoproteomics of urinary exosomes.
An empirical framework for binary interactome mapping.
Shifted Transversal Design smart-pooling for high coverage interactome mapping.
A human MAP kinase interactome.
Analysis of proteomic changes induced upon cellular differentiation of the human intestinal cell line Caco-2.
Mapping a dynamic innate immunity protein interaction network regulating type I interferon production.
Toward an understanding of the protein interaction network of the human liver.
In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.
Autophagic clearance of polyQ proteins mediated by ubiquitin-Atg8 adaptors of the conserved CUET protein family.
A proteome-scale map of the human interactome network.
Widespread macromolecular interaction perturbations in human genetic disorders.
Tom1 Modulates Binding of Tollip to Phosphatidylinositol 3-Phosphate via a Coupled Folding and Binding Mechanism.
An inter-species protein-protein interaction network across vast evolutionary distance.
An ER-Associated Pathway Defines Endosomal Architecture for Controlled Cargo Transport.
Dominant TOM1 mutation associated with combined immunodeficiency and autoimmune disease.
Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations.
A reference map of the human binary protein interactome.
Interactome Mapping Provides a Network of Neurodegenerative Disease Proteins and Uncovers Widespread Protein Aggregation in Affected Brains.
Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.
Global Proximity Interactome of the Human Macroautophagy Pathway.
OpenCell: Endogenous tagging for the cartography of human cellular organization.
Multimodal cell maps as a foundation for structural and functional genomics.
IRAK4 is activated by autophosphorylation
IRAK2 is phosphorylated downstream of IRAK4 following IL1 receptor activation
IRAK1 binds to MYD88 within the IL1R complex
IRAK4 phosphorylates IRAK1
IRAK4-activated IRAK1 autophosphorylates
Hyperphosphorylated IRAK1 associates with TRAF6
The Interleukin 1 receptor complex binds Tollip
TRAF6 binding leads to IRAK1:TRAF6 release
Exocytosis of specific granule lumen proteins
Exocytosis of azurophil granule lumen proteins
Falcon deep research synthesis for TOLLIP