SGD gene description for UBC9 (yeast)
Smt3/SUMO and Ubc9 are required for efficient APC/C-mediated proteolysis in budding yeast.
-
ubc9-2 and smt3-331 mutants are defective in efficient degradation of Pds1 and mitotic cyclins, but not of non-APC/C substrates.
"Both ubc9-2 and smt3-331 mutants were defective in efficient degradation of Pds1 and mitotic cyclins, whereas proteolysis of unstable proteins that are not APC/C substrates was unaffected."
Annotation inferences using phylogenetic trees
Electronic Gene Ontology annotations created by ARBA machine learning models
Combined Automated Annotation using Multiple IEA Methods
A comprehensive analysis of protein-protein interactions in Saccharomyces cerevisiae.
A comprehensive two-hybrid analysis to explore the yeast protein interactome.
A Role for SUMO in meiotic chromosome synapsis.
High-quality binary protein interaction map of the yeast interactome network.
The social and structural architecture of the yeast protein interactome.
Role of a ubiquitin-conjugating enzyme in degradation of S- and M-phase cyclins.
Ubc9p is the conjugating enzyme for the ubiquitin-like protein Smt3p.
The ubiquitin-like proteins SMT3 and SUMO-1 are conjugated by the UBC9 E2 enzyme.
RAD6-dependent DNA repair is linked to modification of PCNA by ubiquitin and SUMO.
Yeast Ull1/Siz1 is a novel SUMO1/Smt3 ligase for septin components and functions as an adaptor between conjugating enzyme and substrates.
An E3-like factor that promotes SUMO conjugation to the yeast septins.
Ubc9 sumoylation controls SUMO chain formation and meiotic synapsis in Saccharomyces cerevisiae.
UniProt entry for S. cerevisiae UBC9 (P50623)
PANTHER subfamily placement and active-site check for UBC9