GO_REF:0000002
Gene Ontology annotation through association of InterPro records with GO terms
GO_REF:0000024
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
GO_REF:0000033
Annotation inferences using phylogenetic trees
GO_REF:0000052
Gene Ontology annotation based on curation of immunofluorescence data
GO_REF:0000107
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
GO_REF:0000117
Electronic Gene Ontology annotations created by ARBA machine learning models
GO_REF:0000120
Combined Automated Annotation using Multiple IEA Methods
PMID:11350182
Molecular and enzymatic characterization of a unique carnitine palmitoyltransferase 1A mutation in the Hutterite community.
PMID:14517221
Functional and structural basis of carnitine palmitoyltransferase 1A deficiency.
PMID:16651524
The brain-specific carnitine palmitoyltransferase-1c regulates energy homeostasis.
PMID:19946888
Defining the membrane proteome of NK cells.
PMID:21492153
Analysis of proteomic changes induced upon cellular differentiation of the human intestinal cell line Caco-2.
PMID:34800366
Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context.
PMID:38016475
CPT1A induction following epigenetic perturbation promotes MAVS palmitoylation and activation to potentiate antitumor immunity.
PMID:7892212
Human liver mitochondrial carnitine palmitoyltransferase I: characterization of its cDNA and chromosomal localization and partial analysis of the gene.
PMID:9691089
Molecular basis of hepatic carnitine palmitoyltransferase I deficiency.
Reactome:R-HSA-200406
CPT1A transfers PALM to CAR
Reactome:R-HSA-200425
Carnitine shuttle
PMID:9461513
Cloning and characterization of the promoter for the liver isoform of the rat carnitine palmitoyltransferase I (L-CPT I) gene.
PMID:11988095
Adenovirus-mediated overexpression of liver carnitine palmitoyltransferase I in INS1E cells: effects on cell metabolism and insulin secretion.
PMID:12754501
Inhibition of hypothalamic carnitine palmitoyltransferase-1 decreases food intake and glucose production.
PMID:12826662
A single amino acid change (substitution of the conserved Glu-590 with alanine) in the C-terminal domain of rat liver carnitine palmitoyltransferase I increases its malonyl-CoA sensitivity close to that observed with the muscle isoform of the enzyme.
PMID:15489334
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PMID:18349115
A moderate increase in carnitine palmitoyltransferase 1a activity is sufficient to substantially reduce hepatic triglyceride levels.
PMID:19136561
Self-association of transmembrane domain 2 (TM2), but not TM1, in carnitine palmitoyltransferase 1A: role of GXXXG(A) motifs.
PMID:19302064
Modulation of the hepatic malonyl-CoA-carnitine palmitoyltransferase 1A partnership creates a metabolic switch allowing oxidation of de novo fatty acids.
PMID:19332540
Palmitate induces insulin resistance in H4IIEC3 hepatocytes through reactive oxygen species produced by mitochondria.
PMID:19553925
Nonalcoholic hepatic steatosis in Zucker diabetic rats: spontaneous evolution and effects of metformin and fenofibrate.
PMID:21990363
An environment-dependent structural switch underlies the regulation of carnitine palmitoyltransferase 1A.
PMID:24222496
Comparison of the catalytic activities of three isozymes of carnitine palmitoyltransferase 1 expressed in COS7 cells.
PMID:27939985
Dihydroartemisinin protects against alcoholic liver injury through alleviating hepatocyte steatosis in a farnesoid X receptor-dependent manner.
PMID:29425493
Carnitine Palmitoyltransferase 1A Has a Lysine Succinyltransferase Activity.
PMID:30851372
Protective effect and mechanism of Qiwei Tiexie capsule on 3T3-L1 adipocytes cells and rats with nonalcoholic fatty liver disease by regulating LXRα, PPARγ, and NF-κB-iNOS-NO signaling pathways.
PMID:30868489
Berberine Ameliorates High-Fat Diet-Induced Non-Alcoholic Fatty Liver Disease in Rats via Activation of SIRT3/AMPK/ACC Pathway.
PMID:31639005
Therapeutic effect and autophagy regulation of myriocin in nonalcoholic steatohepatitis.
PMID:31748600
PCSK9 inhibition as a novel therapeutic target for alcoholic liver disease.
PMID:31901136
Modulation effects of black-vinegar-based supplement against a high-fat dietary habit: antiobesity/hypolipidemic, antioxidative, and energy-metabolism effects.
PMID:31918260
Hepatoprotective effect of different combinations of 18α-and 18β-Glycyrrhizic acid against CCl(4)-induced liver injury in rats.
PMID:31930271
The preventive effect of phenolic-rich extracts from Chinese sumac fruits against nonalcoholic fatty liver disease in rats induced by a high-fat diet.
PMID:31953200
Study on the protection of water extracts of Polygoni Multiflori Radix and Polygoni Multiflori Radix Praeparata against NAFLD and its mechanism.
PMID:33310031
WY14643 improves left ventricular myocardial mitochondrial and systolic functions in obese rats under chronic persistent hypoxia via the PPARα pathway.
file:human/CPT1A/CPT1A-source-evidence.yaml
CPT1A source reconciliation, experimental scope and evidence index