ndk1 (SPAC806.07; UniProt P49740) notes

Experimental (S. pombe)

• Izumiya & Yamamoto 1995 (abstract-only): PMID:7499258; PMID:7499258; C116 allele PMID:7499258 and acts dominant-negatively on mating PMID:7499258.
• Activity: [UniProt:P49740 "Reaction=a ribonucleoside 5'-diphosphate + ATP = a ribonucleoside 5'-"]; [UniProt:P49740 "FUNCTION: Major role in the synthesis of nucleoside triphosphates other"].

Location

• HDA cytosol + nucleus (PMID:16823372). Mitochondrion IBA and IMS ISO derive from S. cerevisiae Ynk1 PMID:12472466; untested in S. pombe -> non-core.

GO-CAMs

• 69a0c46f00003691: two ndk1 activities (GO:0004550, cytosol), part_of UTP biosynthesis (GO:0006228) and CTP biosynthesis (GO:0006241).
• 6796b94c00000009 (phospholipid synthesis): GO:0004550 part_of CTP biosynthesis (CTP for CDP-DAG/CDP-choline/ethanolamine).
• Consistent with review; core BPs chosen as GO:0009142 + GO:0006228 to match S. cerevisiae YNK1 review.

Decisions

• All MF/BP rows accepted; IMP CTP biosynthetic process deferred to curator (full text unavailable).
• Nucleus, mitochondrion, IMS kept non-core.