GO_REF:0000002

Gene Ontology annotation through association of InterPro records with GO terms

GO_REF:0000117

Electronic Gene Ontology annotations created by ARBA machine learning models

GO_REF:0000118

TreeGrafter-generated GO annotations

GO_REF:0000120

Combined Automated Annotation using Multiple IEA Methods

file:PSEPK/pssA/pssA-uniprot.txt

UniProt record for pssA (Q88GQ4)

The record identifies CDP-diacylglycerol--serine O-phosphatidyltransferase, EC 2.7.8.8, while also exposing conflicting InterPro-derived PgsA/cardiolipin GO mappings.

file:PSEPK/pssA/pssA-notes.md

Manual evidence notes for pssA

The notes compare the distinct PssA, PgsA, and Psd reactions and document removal of the cross-mapped annotations.

file:PSEPK/pssA/pssA-deep-research-openscientist.md

OpenScientist deep research for pssA

The report supports the phosphatidylserine-synthase reaction and PLD architecture; its bacterial type label is corrected against primary literature in the manual notes.

PMID:179992

Phosphatidylserine synthetase mutants of Escherichia coli. Genetic mapping and membrane phospholipid composition.

E. coli pss mutants lose phosphatidylethanolamine and accumulate phosphatidylglycerol and cardiolipin.

file:ECOLI/pssA/pssA-uniprot.txt

UniProt record for E. coli pssA (P23830)

PMID:39693441

Structural basis for membrane association and catalysis by phosphatidylserine synthase in Escherichia coli

The primary structure study defines PLD-superfamily PssA as type I and characterizes its peripheral membrane association and catalytic mechanism.