GO_REF:0000104

Electronic Gene Ontology annotations created by transferring manual GO annotations between related proteins based on shared sequence features

Transfers the broad nucleotide binding term, which is redundant with the more specific ATP binding annotation.

GO_REF:0000108

Automatic assignment of GO terms using logical inference, based on on inter-ontology links

Correctly infers MAPK cascade involvement from the MAP kinase activity annotation via inter-ontology logical links.

GO_REF:0000116

Automatic Gene Ontology annotation based on Rhea mapping

Correctly maps the Rhea-curated serine phosphorylation reaction to protein serine kinase activity.

GO_REF:0000117

Electronic Gene Ontology annotations created by ARBA machine learning models

ARBA assigns the broad signal transduction term, which is redundant with the more specific MAPK cascade annotation.

GO_REF:0000120

Combined Automated Annotation using Multiple IEA Methods

Correctly recovers both MAP kinase activity and ATP binding from multiple IEA sources including InterPro and EC number mapping.

file:CUCME/A0A1S3BTE3/A0A1S3BTE3-uniprot.txt

UniProt entry A0A1S3BTE3

Identifies the protein as a mitogen-activated protein kinase with EC:2.7.11.24.
Records catalytic activity for both serine and threonine phosphorylation using ATP.
Classifies the protein in the CMGC Ser/Thr protein kinase family, MAP kinase subfamily.
Identifies the CDD domain STKc_TDY_MAPK, indicating a Group D MAPK with TDY activation loop motif.