Gene Ontology annotation through association of InterPro records with GO terms
Annotation inferences using phylogenetic trees
Electronic Gene Ontology annotations created by ARBA machine learning models
Combined Automated Annotation using Multiple IEA Methods
Impaired prothrombinase activity of factor X Gly381Asp results in severe familial CRM+ FX deficiency.
The human plasma proteome: a nonredundant list developed by combination of four separate sources.
Lipid-bound factor Xa regulates tissue factor activity.
Formation of tissue factor-factor VIIa-factor Xa complex induces activation of the mTOR pathway which regulates migration of human breast cancer cells.
Basis for the specificity and activation of the serpin protein Z-dependent proteinase inhibitor (ZPI) as an inhibitor of membrane-associated factor Xa.
Isolation and characterization of human blood-coagulation factor X cDNA.
A reference map of the human binary protein interactome.
Mechanism of inhibition of activated protein C by protein C inhibitor.
Characterization of a cDNA coding for human factor X.
prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (prothrombinase catalyst)
factor Va + factor Xa -> Va:Xa complex (prothrombinase)
prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst)
factor VII -> factor VIIa
factor X -> factor Xa + factor X activation peptide (VIIIa:IXa catalyst)
Furin cleaves pro-factor X to factor X
Gamma-carboxy pro-factor X transport from the endoplasmic reticulum to the Golgi apparatus
GGCX gamma-carboxylates 3D-F10(32-179) (pro-factor X light chain)
Factor Xa inhibitors binds Xa
Factor Xa inhibitors bind Va:Xa
Hyperactivation of factor X by FVIIIa:FIXa R384L
FVIIIa variant:FIXa does not convert FX to the active FXa
FIXa variant:FVIIIa does not convert FX to the active FXa
factor X -> factor Xa + factor X activation peptide (emicizumab:FIXa catalyst)
factor V -> factor Va intermediate + factor V activation peptide (FXa catalyst)
TF:FVIIa:FXa ->TF:FVIIa + FXa
TF:FVII+FX -> TF:FVII:FXa + FX activation peptide (TF:F7 catalyst)
TF:FVIIa+FX -> TF:FVIIa:FXa + FX activation peptide (TF:F7a catalyst)
factor VIII -> factor VIIIa + factor VIII B chain+ factor VIII A3 acidic polypeptide +VWF multimer (TF:FVIIa:FXa catalyst)
TF:FVII:FXa ->TF:FVIIa:FXa (FXa catalyst)
TFPIα:FV intermediate:PROS1 binds TF:FVIIa:FXa
factor Va intermediate + factor Xa -> factor Va intermediate:factor Xa
Identification of exosite residues of factor Xa involved in recognition of PAR-2 on endothelial cells.
Ixolaris binding to factor X reveals a precursor state of factor Xa heparin-binding exosite.
Molecular basis of vitamin-K-driven γ-carboxylation at the membrane interface.
Structural basis for chemical inhibition of human blood coagulation factor Xa.