Gene Ontology annotation through association of InterPro records with GO terms
Gene Ontology annotation based on Enzyme Commission mapping
Combined Automated Annotation using Multiple IEA Methods
UniProtKB Q88MC3 histidine kinase entry
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GacS is a membrane-associated histidine kinase
"-!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000256|ARBA:ARBA00004429}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004429}."
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GacS is annotated with histidine kinase catalytic activity
"-!- CATALYTIC ACTIVITY: Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L- histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};"
Identification of reciprocal adhesion genes in pathogenic and non-pathogenic Pseudomonas.
Transcriptional organization and regulation of the Pseudomonas putida K1 type VI secretion system gene cluster.
Engineering glucose metabolism for enhanced muconic acid production in Pseudomonas putida KT2440.
Adaptive laboratory evolution and genetic engineering improved terephthalate utilization in Pseudomonas putida KT2440.
Curated notes on gacS in Pseudomonas putida KT2440
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The core molecular role is membrane phosphorelay sensor kinase activity
"The core molecular role is phosphorelay sensor kinase activity at the membrane."
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Adhesion and K1-T6SS regulation are downstream outputs of global GacS signaling
"Process terms should center on phosphorelay signal transduction; the documented adhesion and T6SS phenotypes are downstream outputs of that global signaling role rather than separate direct molecular activities."