ppc1 (Q9USK7, SPCC4B3.18) notes
Role: phosphopantothenoylcysteine synthetase (PPCS); module coenzyme_a_biosynthesis.
Fetch: just fetch-gene SCHPO ppc1 FAILED (UniProt entry YJ2I_SCHPO is still "Uncharacterized protein C4B3.18" with no gene name); refetched with -u Q9USK7.
Evidence
- PMID:23091701
- PMID:23091701
- PMID:23091701
- Whole-cell GFP localisation (cytoplasm + nucleus) PMID:23091701.
- UniProt PANTHER family PTHR12290 carries the name "CORNICHON-RELATED" (a PANTHER family-name quirk); the module correctly uses subfamily PTHR12290:SF2.
- Nucleotide specificity (ATP vs CTP) unknown for the S. pombe enzyme.
Decisions
- Nucleus rows non-core (nuclear phenotypes are secondary to low acetyl-CoA). All MF/BP/cytoplasm rows accepted.
- Core: GO:0004632 / GO:0015937 / GO:0005829 — matches S. cerevisiae CAB2 review (no CoA-SPC complex term: no S. pombe evidence).