Gene Ontology annotation through association of InterPro records with GO terms
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Auxin polar transport and flower formation in Arabidopsis thaliana transformed with indoleacetamide hydrolase (iaaH) gene.
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The cached abstract concerns auxin polar transport and flower formation in pin/iaaH material and does not provide visible GI-specific evidence.
"Involvement of auxin polar transport in flower formation of Arabidopsis thaliana was studied using a pinformed (pin) mutant (Rpin) transformed with the indoleacetamide hydrolase (iaaH) gene"
GIGANTEA is a nuclear protein involved in phytochrome signaling in Arabidopsis.
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GI-GFP fusion experiments showed nucleoplasmic localization and linked GI to phytochrome B signaling.
"Optical sectioning by using the green fluorescent protein-GI fusion protein showed green fluorescence throughout the nucleoplasm."
SPINDLY and GIGANTEA interact and act in Arabidopsis thaliana pathways involved in light responses, flowering, and rhythms in cotyledon movements.
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GI interacts with SPY and genetic data place SPY and GI in overlapping flowering, light-response, and cotyledon-rhythm pathways.
"GI and SPY also interacted in Escherichia coli and in vitro pull-down assays."
Distinct roles of GIGANTEA in promoting flowering and regulating circadian rhythms in Arabidopsis.
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GI promotes long-day flowering by increasing CO and FT expression, and it has a distinct general role in circadian rhythm regulation.
"These experiments demonstrated that GI acts between the circadian oscillator and CO to promote flowering by increasing CO and FT mRNA abundance."
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Functional GI:GFP localizes to the nucleus in transgenic Arabidopsis.
"Functional GI:green fluorescent protein is localized to the nucleus in transgenic Arabidopsis plants"
Involvement of GIGANTEA gene in the regulation of the cold stress response in Arabidopsis.
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GI is induced by cold stress and positively contributes to freezing tolerance through a CBF-independent pathway.
"These results suggest that GI gene positively regulates freezing tolerance via a CBF-independent pathway."
The molecular basis of temperature compensation in the Arabidopsis circadian clock.
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GI contributes to circadian temperature compensation and rhythmic robustness over physiological temperature ranges.
"At 27 degrees C, a dynamic balance between GI and LHY allows temperature compensation in wild-type plants, but circadian function is impaired in lhy and gi mutant plants."
ZEITLUPE is a circadian photoreceptor stabilized by GIGANTEA in blue light.
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GI directly interacts with and stabilizes ZTL in a blue-light-enhanced mechanism required for robust TOC1 rhythms.
"GI, a large plant-specific protein with a previously undefined molecular role, stabilizes ZTL in vivo."
FKF1 and GIGANTEA complex formation is required for day-length measurement in Arabidopsis.
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FKF1 and GI form a blue-light-dependent complex that controls CO transcription through CDF1 stability and CO chromatin association.
"We demonstrate that FKF1 and GI proteins form a complex in a blue-light-dependent manner."
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GI interacts with CDF1 and the GI-FKF1-CDF1 module associates with CO chromatin.
"GI, FKF1, and CDF1 proteins associate with CO chromatin."
Acceleration of flowering during shade avoidance in Arabidopsis alters the balance between FLOWERING LOCUS C-mediated repression and photoperiodic induction of flowering.
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Low red:far-red acceleration of flowering depends on the photoperiod pathway genes GI and CO in long days.
"A low red to far-red ratio required the photoperiod-pathway genes GIGANTEA (GI) and CONSTANS (CO) to fully accelerate flowering in long days and did not promote flowering in short days."
COP1 and ELF3 control circadian function and photoperiodic flowering by regulating GI stability.
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COP1 and ELF3 regulate circadian function and photoperiodic flowering by modulating GI stability and accumulation.
"We propose a model in which ELF3 acts as a substrate adaptor, enabling COP1 to modulate light input signal to the circadian clock through targeted destabilization of GI."
Proteomic profiling of tandem affinity purified 14-3-3 protein complexes in Arabidopsis thaliana.
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TAP-MS of 14-3-3 omega complexes identified many putative clients, but the GI-specific supplemental evidence is not visible in the cached text.
"The identification here of 121 putative clients provides support for in vivo 14-3-3 interactions with a diverse array of proteins"
GIGANTEA directly activates Flowering Locus T in Arabidopsis thaliana.
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GI expressed in mesophyll or vascular tissues increases FT expression and GI binds FT repressors SVP, TEM1, and TEM2 near the FT promoter.
"We found that GI can bind to three FT repressors: SHORT VEGETATIVE PHASE (SVP), TEMPRANILLO (TEM)1, and TEM2."
Extensive signal integration by the phytohormone protein network.
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The study generated a large Arabidopsis phytohormone signaling protein-protein interaction network; GI-specific interactions require unavailable supplemental detail to assess.
"Here, we experimentally generated a systems-level map of the Arabidopsis phytohormone signalling network, consisting of more than 2,000 binary protein-protein interactions."
GIGANTEA functions as a co-repressor of cold stress response with a histone-modifying complex.
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GI acts with HOS15 and HD2C as a cold-response co-repressor affecting histone acetylation and CBF binding at COR promoters.
"We further demonstrate that GI forms a co-repressor with HOS15 and HD2C, inhibiting CBF binding and preventing COR gene activation under normal conditions."
Oxidative stress tolerance and longevity in Arabidopsis: the late-flowering mutant gigantea is tolerant to paraquat.
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gi mutants show increased tolerance to paraquat-induced oxidative stress and gi-3 is more tolerant to hydrogen peroxide.
"In addition, the gi-3 mutant was more tolerant to hydrogen peroxide."
UniProtKB Q9SQI2 local record for Arabidopsis GIGANTEA
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UniProt summarizes GI as a nuclear and cytoplasmic GIGANTEA-family protein involved in circadian rhythm and photoperiodic flowering, with documented interactions with SPY, ZTL-family proteins, CDF1, and TCP4.
"FUNCTION: Involved in regulation of circadian rhythm and photoperiodic flowering."
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UniProt subcellular-location vocabulary maps GI to nucleus and cytoplasm.
"SUBCELLULAR LOCATION: Nucleus. Cytoplasm."
Falcon deep literature research for Arabidopsis GI
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The deep-research synthesis frames GI as a plant-specific, timing-dependent protein interaction hub/scaffold that integrates circadian, photoperiodic, light-quality, and stress-response pathways.
PANTHER PTHR36319 family entries for GIGANTEA proteins