Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
Combined Automated Annotation using Multiple IEA Methods.
Anti-CRISPR-Associated Proteins Are Crucial Repressors of Anti-CRISPR Transcription
The autoregulator Aca2 mediates anti-CRISPR repression
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Aca2 is a dimer that represses the acrIF8-aca2 operon
"Aca2 is a dimer that represses the expression of the acrIF8–aca2 operon, and that this autoregulation is mediated through binding to inverted repeats in the promoter region"
Structural basis for anti-CRISPR repression mediated by bacterial operon proteins Aca1 and Aca2
Crystal structure of the anti-CRISPR repressor Aca2
Phage anti-CRISPR control by an RNA- and DNA-binding helix-turn-helix protein
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Aca2 uses HTH domain for both DNA and RNA binding
"the HTH domain of the regulator Aca2, in addition to repressing Acr synthesis transcriptionally through DNA binding, inhibits translation of mRNAs by binding conserved RNA stem-loops and blocking ribosome access"
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Aca2 inhibits translation by blocking ribosome access to mRNA
"the HTH domain of the regulator Aca2, in addition to repressing Acr synthesis transcriptionally through DNA binding, inhibits translation of mRNAs by binding conserved RNA stem-loops and blocking ribosome access"
Deep research on ACA2 function