Gene Ontology annotation through association of InterPro records with GO terms

InterPro2GO mapping electronically transfers GO terms (e.g. nucleotide binding, defense response) onto RPM1 from its NB-ARC and LRR InterPro signatures; useful for breadth but not RPM1-specific function.

Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt

UniProt SubcellularLocation-to-GO mapping yields plasma membrane localization for RPM1, consistent with peripheral plasma-membrane localization reported experimentally.

GO_REF:0000117

Electronic Gene Ontology annotations created by ARBA machine learning models

ARBA machine-learning rules propagate broad NLR-family annotations to RPM1; treated as supporting context rather than as primary evidence of the RIN4-guard mechanism.

PMID:11955429

RIN4 interacts with Pseudomonas syringae type III effector molecules and is required for RPM1-mediated resistance in Arabidopsis.

RIN4 interacts with AvrB, AvrRpm1, and RPM1 and is required for RPM1-mediated resistance.

PMID:15722472

RIN13 is a positive regulator of the plant disease resistance protein RPM1.

RIN13 is a positive regulator of RPM1-mediated immunity but does not define RPM1 core molecular activity.

PMID:16212605

A duplicated pair of Arabidopsis RING-finger E3 ligases contribute to the RPM1- and RPS2-mediated hypersensitive response.

RING-finger E3 ligases contribute to RPM1- and RPS2-mediated hypersensitive response outputs.

PMID:20332379

Endosome-associated CRT1 functions early in resistance gene-mediated defense signaling in Arabidopsis and tobacco.

CRT1 functions early in resistance-gene-mediated defense signaling and is an RPM1-associated immune regulator.

PMID:38358510

The RIN4-like/NOI proteins NOI10 and NOI11 modulate the response to biotic stresses mediated by RIN4 in Arabidopsis.

RIN4-like/NOI proteins modulate RIN4-mediated biotic stress responses relevant to RPM1 signaling context.

PMID:7638602

Structure of the Arabidopsis RPM1 gene enabling dual specificity disease resistance.

RPM1 encodes an NB-LRR disease-resistance protein enabling dual specificity to Pseudomonas syringae avrRpm1 and avrB.

PMID:8768370

Expression of the Pseudomonas syringae avirulence protein AvrB in plant cells alleviates its dependence on the hypersensitive response and pathogenicity (Hrp) secretion system in eliciting genotype-specific hypersensitive cell death.

Intracellular AvrB expression triggers RPM1-dependent hypersensitive cell death.

PMID:9861059

The Arabidopsis thaliana RPM1 disease resistance gene product is a peripheral plasma membrane protein that is degraded coincident with the hypersensitive response.

RPM1 is a peripheral plasma membrane protein likely residing on the cytoplasmic face of the plasma membrane and degraded coincident with HR.

file:ARATH/RPM1/RPM1-deep-research-falcon.md

Falcon deep research for Arabidopsis RPM1

RPM1 is a plasma-membrane-associated CNL immune receptor that guards RIN4 and is activated by effector-induced RIN4 modification.
RPM1 localization and immune recognition are organized at the cytoplasmic face of the plasma membrane.

file:ARATH/RPM1/RPM1-uniprot.txt

UniProt record for Arabidopsis RPM1

UniProt identifies RPM1/Q39214 as a disease resistance NB-LRR protein with plasma membrane, ADP/ATP binding, and hypersensitive response annotations.

file:interpro/panther/PTHR23155/PTHR23155-entries.csv

PANTHER PTHR23155 disease resistance protein RP family entries

PTHR23155 places Arabidopsis Q39214/RPM1 in disease resistance protein RPM1 subfamily SF1205.