GO_REF:0000002
Gene Ontology annotation through association of InterPro records with GO terms
GO_REF:0000024
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
GO_REF:0000033
Annotation inferences using phylogenetic trees
GO_REF:0000052
Gene Ontology annotation based on curation of immunofluorescence data
GO_REF:0000107
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
GO_REF:0000120
Combined Automated Annotation using Multiple IEA Methods
PMID:11485735
Enhanced CD4+ T cell proliferation and Th2 cytokine production in DR6-deficient mice.
PMID:12515813
Enhanced B cell expansion, survival, and humoral responses by targeting death receptor 6.
PMID:19225519
APP binds DR6 to trigger axon pruning and neuron death via distinct caspases.
PMID:19654028
Functional analysis of the posttranslational modifications of the death receptor 6.
PMID:21725297
Death receptor 6 negatively regulates oligodendrocyte survival, maturation and myelination.
PMID:22761420
Death receptor 6 induces apoptosis not through type I or type II pathways, but via a unique mitochondria-dependent pathway by interacting with Bax protein.
PMID:23559013
A DR6/p75(NTR) complex is responsible for β-amyloid-induced cortical neuron death.
PMID:24806670
Genetic analysis reveals that amyloid precursor protein and death receptor 6 function in the same pathway to control axonal pruning independent of β-secretase.
PMID:25898930
Death Receptor 6 and Caspase-6 Regulate Prion Peptide-Induced Axonal Degeneration in Rat Spinal Neurons.
PMID:28285993
Death Receptor 6 Promotes Wallerian Degeneration in Peripheral Axons.
PMID:32296183
A reference map of the human binary protein interactome.
PMID:35922511
A physical wiring diagram for the human immune system.
PMID:38110576
Retraction Note: APP binds DR6 to trigger axon pruning and neuron death via distinct caspases.
PMID:41891813
Death receptor 6 does not regulate axon degeneration and Schwann cell injury responses during Wallerian degeneration.
Reactome:R-HSA-1989771
Expression of TNFRSF21