Annotation inferences using phylogenetic trees
Electronic Gene Ontology annotations created by ARBA machine learning models
Pseudomonas aeruginosa EftM Is a Thermoregulated Methyltransferase.
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Purified EftM trimethylates EF-Tu exclusively at Lys5 with SAM as donor; activity is lost after preincubation at 37 degrees C; the G50R variant lacks SAM binding and activity.
"A natural variant of EftM, with a glycine to arginine substitution at position 50 in the predicted SAM-binding domain, lacks both SAM binding and enzyme activity."
UniProt record Q9HWK3 (PA4178)