Annotation inferences using phylogenetic trees

Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt

Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara

Automatic assignment of GO terms using logical inference, based on on inter-ontology links

Electronic Gene Ontology annotations created by ARBA machine learning models

Combined Automated Annotation using Multiple IEA Methods

The targeting of cystinosin to the lysosomal membrane requires a tyrosine-based signal and a novel sorting motif.

Cystinosin, the protein defective in cystinosis, is a H(+)-driven lysosomal cystine transporter.

Expression of CTNS alleles: subcellular localization and aminoglycoside correction in vitro.

Immunolocalization of cystinosin, the protein defective in cystinosis.

Molecular pathogenesis of cystinosis: effect of CTNS mutations on the transport activity and subcellular localization of cystinosin.

Altered status of glutathione and its metabolites in cystinotic cells.

Decreased intracellular ATP content and intact mitochondrial energy generating capacity in human cystinotic fibroblasts.

Non-verbal deficits in young children with a genetic metabolic disorder: WPPSI-III performance in cystinosis.

Integral and associated lysosomal membrane proteins.

Identification and subcellular localization of a new cystinosin isoform.

Large-scale proteomics and phosphoproteomics of urinary exosomes.

Mechanism of proton/substrate coupling in the heptahelical lysosomal transporter cystinosin.

Cystinosin is a melanosomal protein that regulates melanin synthesis.

Lysosomal Targeting of Cystinosin Requires AP-3.

Carboxyl-Terminal SSLKG Motif of the Human Cystinosin-LKG Plays an Important Role in Plasma Membrane Sorting.

Impact of Cystinosin Glycosylation on Protein Stability by Differential Dynamic Stable Isotope Labeling by Amino Acids in Cell Culture (SILAC).

Structure and mechanism of human cystine exporter cystinosin.

Cystine transport is defective in isolated leukocyte lysosomes from patients with cystinosis.

A novel gene encoding an integral membrane protein is mutated in nephropathic cystinosis.

Miscellaneous transport and binding events

CTNS cotransports CySS-, H+ from lysosomal lumen to cytosol

SLC-mediated transport of oligopeptides