Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Gene Ontology annotation based on curation of immunofluorescence data
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Automatic assignment of GO terms using logical inference, based on on inter-ontology links
Electronic Gene Ontology annotations created by ARBA machine learning models
Coupling of coat assembly and vesicle budding to packaging of putative cargo receptors.
Localization and recycling of gp27 (hp24gamma3): complex formation with other p24 family members.
Decoding of sorting signals by coatomer through a GTPase switch in the COPI coat complex.
Coupled transport of p24 family members.
Oligomeric state and stoichiometry of p24 proteins in the early secretory pathway.
Evidence for a role of transmembrane protein p25 in localization of protein tyrosine phosphatase TC48 to the ER.
TMP21 is a presenilin complex component that modulates gamma-secretase but not epsilon-secretase activity.
Proteomic and bioinformatic characterization of the biogenesis and function of melanosomes.
The cargo receptors Surf4, endoplasmic reticulum-Golgi intermediate compartment (ERGIC)-53, and p25 are required to maintain the architecture of ERGIC and Golgi.
GPI glycan remodeling by PGAP5 regulates transport of GPI-anchored proteins from the ER to the Golgi.
Selective export of human GPI-anchored proteins from the endoplasmic reticulum.
Proteinase-activated receptors, nucleotide P2Y receptors, and μ-opioid receptor-1B are under the control of the type I transmembrane proteins p23 and p24A in post-Golgi trafficking.
Syntaxin 17 cycles between the ER and ERGIC and is required to maintain the architecture of ERGIC and Golgi.
The enterohemorrhagic Escherichia coli effector protein NleF binds mammalian Tmp21.
Quantitative interaction proteomics of neurodegenerative disease proteins.
RAB21 interacts with TMED10 and modulates its localization and abundance.
A Translocation Pathway for Vesicle-Mediated Unconventional Protein Secretion.
Interactome Mapping Provides a Network of Neurodegenerative Disease Proteins and Uncovers Widespread Protein Aggregation in Affected Brains.
Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.
OpenCell: Endogenous tagging for the cartography of human cellular organization.
Multimodal cell maps as a foundation for structural and functional genomics.
Involvement of the transmembrane protein p23 in biosynthetic protein transport.
gp25L/emp24/p24 protein family members of the cis-Golgi network bind both COP I and II coatomer.
SEC31:SEC13 and v-SNARE recruitment
Nucleotide exchange on RAB1
TMED2:TMED10 tetramer binds GPI anchored proteins
SEC16 complex binds SAR1B:GTP:SEC23:SEC24
RAB1:GTP binds USO1 and GORASP1:GOLGA2
COPII coat binds TRAPPCII and RAB1:GDP
CSNK1D phosphorylates SEC23
BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle
Inner coat assembly and cargo binding
ARFGAP, cargo, v-SNAREs and p24 proteins bind nascent COPI complex
ARFGAPs stimulate ARF GTPase activity
ERGIC-to-Golgi vesicles bind dynein:dynactin
Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex
cis-Golgi t-SNAREs bind YKT6 on tethered vesicle
ARFGAP, cargo, vSNARES and p24 proteins bind COPI vesicles at Golgi
ARFGAPs stimulate ARF GTPase activity at the Golgi membrane
Retrograde vesicle is tethered at the ER by the NRZ complex and t-SNAREs
Retrograde COPI vesicles bind kinesin and microtubules
COPI vesicle uncoating at the ER
UniProt record P49755 (TMEDA_HUMAN)