Gene Ontology annotation through association of InterPro records with GO terms
Annotation inferences using phylogenetic trees
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Electronic Gene Ontology annotations created by ARBA machine learning models
Combined Automated Annotation using Multiple IEA Methods
Dissecting and designing inhibitor selectivity determinants at the S1 site using an artificial Ala190 protease (Ala190 uPA).
Design of selective phenylglycine amide tissue factor/factor VIIa inhibitors.
TF/FVIIa transactivate PDGFRbeta to regulate PDGF-BB-induced chemotaxis in different cell types: involvement of Src and PLC.
Formation of tissue factor-factor VIIa-factor Xa complex induces activation of the mTOR pathway which regulates migration of human breast cancer cells.
MicroRNA-19b functions as potential anti-thrombotic protector in patients with unstable angina by targeting tissue factor.
Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver.
Using an in situ proximity ligation assay to systematically profile endogenous protein-protein interactions in a pathway network.
Nucleotide sequence of the gene coding for human factor VII, a vitamin K-dependent protein participating in blood coagulation.
Affinity purification of human tissue factor: interaction of factor VII and tissue factor in detergent micelles.
Structural and functional characterization of novel F7 mutations identified in Chinese factor VII-deficient patients.
The crystal structure of the complex of blood coagulation factor VIIa with soluble tissue factor.
Structural integrity of the gamma-carboxyglutamic acid domain of human blood coagulation factor IXa Is required for its binding to cofactor VIIIa.
Factor VII central. A novel mutation in the catalytic domain that reduces tissue factor binding, impairs activation by factor Xa, and abolishes amidolytic and coagulant activity.
Factor VII deficiency caused by a structural variant N57D of the first epidermal growth factor domain.
tissue factor (TF) + activated factor VII (F7a) -> TF:F7a complex
factor VII -> factor VIIa
tissue factor (TF) + factor VII (F7) -> TF:F7 complex
GGCX gamma-carboxylates F7(21-466) (pro-factor VII)
Gamma-carboxy pro-factor VII transport from the endoplasmic reticulum to the Golgi apparatus
Furin cleaves pro-factor VII to factor VII
TF:FVIIa:FXa ->TF:FVIIa + FXa
TF:FVII+FX -> TF:FVII:FXa + FX activation peptide (TF:F7 catalyst)
TF:FVIIa+FX -> TF:FVIIa:FXa + FX activation peptide (TF:F7a catalyst)
factor VIII -> factor VIIIa + factor VIII B chain+ factor VIII A3 acidic polypeptide +VWF multimer (TF:FVIIa:FXa catalyst)
TF:FVIIa+FIX -> TF:FVIIa:FIXa + FIX activation peptide (TF:F7a catalyst)
TF:FVIIa:FIXa ->TF:FVIIa + FIXa
TF:FVII:FXa ->TF:FVIIa:FXa (FXa catalyst)
TFPIα:FV intermediate:PROS1 binds TF:FVIIa:FXa
Ixodes ricinus Salivary Serpin Iripin-8 Inhibits the Intrinsic Pathway of Coagulation and Complement.
Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin or 2,2',4,4',5,5'-hexachlorobiphenyl on vitamin K-dependent blood coagulation in male and female WAG/Rij-rats.
A high fat meal activates blood coagulation factor VII in rats.
Cloning and expression of rat coagulation factor VII.
Expression of MRP2 and MRP3 during liver regeneration after 90% partial hepatectomy in rats.
Alcohol-free red wine prevents arterial thrombosis in dietary-induced hypercholesterolemic rats: experimental support for the 'French paradox'.
[Expression of fusion protein encoding EGFP-EGF1 of rat coagulation factor VII and its binding function].
Effects of the hormones of the thyroid axis on the vitamin K-dependent plasma factors of blood coagulation (II, VII, IX, and X).
Genistein alters coagulation gene expression in ovariectomised rats treated with phytoestrogens.
Hormones of hypothalamic-pituitary-thyroid axis are significant regulators of synthesis and secretion of vitamin K-dependent plasma coagulation factors.
Anticoagulatory and antiinflammatory effects of astaxanthin in diabetic rats.
Circadian rhythms of blood clotting time and coagulation factors II, VII, IX and X in rats.
Vitamin K-dependent blood clotting changes in female rats treated with oestrogens.
Somatotropin and somatostatin effects on vitamin K-dependent plasma coagulation factors.
Hypercoagulable state in a hypobaric, hypoxic environment causes non-bacterial thrombotic endocarditis in rats.
Mice lacking factor VII develop normally but suffer fatal perinatal bleeding.
Role of hepsin in factor VII activation in zebrafish.
Localization of factor VII (proconvertin) in a microsomal subfraction.
Vitamin K-reversible hypoprothrombinemia in rats. I. Sex differences in the development of hypoprothrombinemia and the effects of beta-lactam antibiotics.
The Effect of Carbon Dioxide Insufflation Applied at Different Pressures and Periods on Thrombotic Factors.
Daily and circadian rhythms of tissue factor pathway inhibitor and factor VII activity.
High affinity Ca(2+)-binding site in the serine protease domain of human factor VIIa and its role in tissue factor binding and development of catalytic activity.