Vps35 (CG5625) notes

Accession: the symbol lookup returned Q7KVL7 (46 GOA rows); the expected accession Q9W277 has more GOA rows and was used (fetched with just fetch-gene DROME Q9W277 --alias Vps35).

• Wls retrieval for Wg secretion PMID:18193037.
• Serpentine retrieval via Rab9 late endosomes in trachea; Rab9 binds Vps35 PMID:23322046.
• Notch cargo PMID:30176986.
• Early endosome with Snx3 PMID:22041890.
• Endocytosis screen in S2 cells PMID:18057029; synaptic vesicle recycling, LRRK2 interplay PMID:28482024; rotenone protection by overexpression PMID:24915984.

Decisions: cargo receptor -> cargo adaptor (contributes_to); obsolete endosome-to-PM transport -> endocytic recycling; synaptic rows non-core; response to rotenone over-annotated (overexpression modifier).
Deep research: falcon completed (Vps35-deep-research-falcon.md) after the initial review; consistent with the review (non-enzymatic retromer scaffold acting on endosomes) [file:DROME/Vps35/Vps35-deep-research-falcon.md "Vps35 performs its sorting function on intracellular endosomal membranes and associated trafficking carriers"]. It adds NMJ pre/postsynaptic localization and APP extracellular-vesicle cargo sorting (Walsh et al. 2021) and wing-epithelium trafficking-hub data, none of which is in GOA. No annotation actions changed.