GO_REF:0000033
Annotation inferences using phylogenetic trees
GO_REF:0000044
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
GO_REF:0000107
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
GO_REF:0000120
Combined Automated Annotation using Multiple IEA Methods
PMID:16502470
Human colostrum: identification of minor proteins in the aqueous phase by proteomics.
PMID:19056867
Large-scale proteomics and phosphoproteomics of urinary exosomes.
PMID:19199708
Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).
PMID:19946888
Defining the membrane proteome of NK cells.
PMID:20458337
MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis.
PMID:20551380
Proteomics characterization of extracellular space components in the human aorta.
PMID:21196491
The Na/K-ATPase is obligatory for membrane anchorage of retinoschisin, the protein involved in the pathogenesis of X-linked juvenile retinoschisis.
PMID:21362503
Protein profile of exosomes from trabecular meshwork cells.
PMID:24769233
Proteomic analysis of cerebrospinal fluid extracellular vesicles: a comprehensive dataset.
PMID:27068509
Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins.
PMID:27559042
Glycoproteomics Reveals Decorin Peptides With Anti-Myostatin Activity in Human Atrial Fibrillation.
PMID:28327460
Comprehensive proteomic characterization of stem cell-derived extracellular matrices.
PMID:36399478
MatrisomeDB 2.0: 2023 updates to the ECM-protein knowledge database.
Reactome:R-HSA-8952289
FAM20C phosphorylates FAM20C substrates
Reactome:R-HSA-976734
Amyloid fibrils have additional components
Reactome:R-HSA-977136
Amyloid precursor proteins form ordered fibrils
PMID:37652017
Human astrocytes and microglia show augmented ingestion of synapses in Alzheimer's disease via MFG-E8.
PMID:10411933
Medin: an integral fragment of aortic smooth muscle cell-produced lactadherin forms the most common human amyloid.
PMID:12000961
Identification of a factor that links apoptotic cells to phagocytes.
PMID:15155946
Autoimmune disease and impaired uptake of apoptotic cells in MFG-E8-deficient mice.
PMID:22357850
MFG-E8 mediates primary phagocytosis of viable neurons during neuroinflammation.
PMID:23647050
Lactadherin/MFG-E8 is essential for microglia-mediated neuronal loss and phagoptosis induced by amyloid β.
PMID:18160406
Crystal structure of lactadherin C2 domain at 1.7A resolution with mutational and computational analyses of its membrane-binding motif.
PMID:19204935
SED1/MFG-E8: a bi-motif protein that orchestrates diverse cellular interactions.
PMID:18008006
Milk fat globule-EGF factor 8/lactadherin plays a crucial role in maintenance and repair of murine intestinal epithelium.
PMID:15834428
Lactadherin promotes VEGF-dependent neovascularization.
PMID:19884654
Mfge8 diminishes the severity of tissue fibrosis in mice by binding and targeting collagen for uptake by macrophages.
PMID:36385530
Medin co-aggregates with vascular amyloid-β in Alzheimer's disease.
PMID:32900929
Medin aggregation causes cerebrovascular dysfunction in aging wild-type mice.
PMID:17123296
Lactadherin detects early phosphatidylserine exposure on immortalized leukemia cells undergoing programmed cell death.
PMID:20213738
Aberrant splicing of the milk fat globule-EGF factor 8 (MFG-E8) gene in human systemic lupus erythematosus.