GO_REF:0000002
Gene Ontology annotation through association of InterPro records with GO terms
GO_REF:0000024
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
GO_REF:0000033
Annotation inferences using phylogenetic trees
GO_REF:0000044
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
GO_REF:0000117
Electronic Gene Ontology annotations created by ARBA machine learning models
GO_REF:0000120
Combined Automated Annotation using Multiple IEA Methods
PMID:17071714
Identification of human tRNA:m5C methyltransferase catalysing intron-dependent m5C formation in the first position of the anticodon of the pre-tRNA Leu (CAA).
PMID:22395603
The tRNA methyltransferase NSun2 stabilizes p16INK⁓ mRNA by methylating the 3'-untranslated region of p16.
PMID:22658674
Insights into RNA biology from an atlas of mammalian mRNA-binding proteins.
PMID:22681889
The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.
PMID:28341602
Cytosolic YB-1 and NSUN2 are the only proteins recognizing specific motifs present in mRNAs enriched in exosomes.
PMID:28418038
5-methylcytosine promotes mRNA export - NSUN2 as the methyltransferase and ALYREF as an m(5)C reader.
PMID:31276587
NSUN2 introduces 5-methylcytosines in mammalian mitochondrial tRNAs.
PMID:31287866
Mammalian NSUN2 introduces 5-methylcytidines into mitochondrial tRNAs.
PMID:31358969
5-methylcytosine promotes pathogenesis of bladder cancer through stabilizing mRNAs.
PMID:33961781
Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.
PMID:34556860
Activity-based RNA-modifying enzyme probing reveals DUS3L-mediated dihydrouridylation.
PMID:34800366
Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context.
PMID:42587746
m5C Methylation of mRNA: Still More Questions Than Answers.
PMID:41707999
The RNA methyltransferase NSUN2 catalyzes 5-methylcytosine (m(5)C) on IL1B mRNA to promote transcript stability.
PMID:31186410
Loss of 5-methylcytosine alters the biogenesis of vault-derived small RNAs to coordinate epidermal differentiation.
PMID:22577224
Whole exome sequencing identifies a splicing mutation in NSUN2 as a cause of a Dubowitz-like syndrome.
Reactome:R-HSA-6785438
NSUN2 methylates cytidine-40, cytidine-48, cytidine-49, cytidine-50 of tRNA(GLY)(GCC)