Gene Ontology annotation through association of InterPro records with GO terms
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Combined Automated Annotation using Multiple IEA Methods
Functional and molecular biological evidence for a possible beta3-adrenoceptor in the human detrusor muscle.
The beta3-adrenergic receptor activates mitogen-activated protein kinase in adipocytes through a Gi-dependent mechanism.
Beta(1)/beta(2)/beta(3)-adrenoceptor knockout mice are obese and cold-sensitive but have normal lipolytic responses to fasting.
Hetero-oligomerization between beta2- and beta3-adrenergic receptors generates a beta-adrenergic signaling unit with distinct functional properties.
Molecular characterization of the mouse beta 3-adrenergic receptor: relationship with the atypical receptor of adipocytes.
Oxygen-regulated beta(2)-adrenergic receptor hydroxylation by EGLN3 and ubiquitylation by pVHL.
Molecular characterization of the human beta 3-adrenergic receptor.
Multiplexed mapping of the interactome of GPCRs with receptor activity-modifying proteins.
Targeted disruption of the beta 3-adrenergic receptor gene.
Pharmacological characterization of a recently described human beta 3-adrenergic receptor mutant.
The negative inotropic effect of beta3-adrenoceptor stimulation is mediated by activation of a nitric oxide synthase pathway in human ventricle.
Polymorphism of the human beta3-adrenoceptor gene forms a well-conserved haplotype that is associated with moderate obesity and altered receptor function.
Liganded Gs-activating GPCR acts as a GEF for Gs
The Ligand:GPCR:Gs complex dissociates
Liganded Gs-activating GPCRs bind inactive heterotrimeric Gs
β-blockers bind ADRB1,2,3
The arrestin domain-containing 3 protein regulates body mass and energy expenditure.
Human Brown Adipocyte Thermogenesis Is Driven by β2-AR Stimulation.
β3-Adrenergic receptors regulate human brown/beige adipocyte lipolysis and thermogenesis.
UniProt entry P13945 (ADRB3_HUMAN)