FMN1 (YDR236C) notes

UniProt Q03778; riboflavin kinase, EC 2.7.1.26 [UniProt:Q03778].

Evidence journal

• Recombinant activity, monofunctional [PMID:10887197 "The purified form of the expressed recombinant protein efficiently catalyzed the formation of FMN from riboflavin and ATP."; "the yeast enzyme did not show accompanying FAD synthetase activity"].
• Deletion rescued by FMN PMID:10887197.
• Location: microsomes (~90%) and mitochondrial inner membrane (~10%), C-terminus in matrix PMID:10887197.
• PMID:12614612 (murine pre-RC two-hybrid) cited by SGD for riboflavin kinase IDA appears to be a wrong PMID.

Decisions

• InterPro2GO riboflavin biosynthetic process REMOVE (kinase consumes riboflavin). Cytosol RCA over-annotated (membrane protein). PMID:12614612 row UNDECIDED.