Gene Ontology annotation through association of InterPro records with GO terms
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Gene Ontology annotation based on curation of immunofluorescence data
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Combined Automated Annotation using Multiple IEA Methods
Novel complex integrating mitochondria and the microtubular cytoskeleton with chromosome remodeling and tumor suppressor RASSF1 deduced by in silico homology analysis, interaction cloning in yeast, and colocalization in cultured cells.
Identification and characterization of human VCY2-interacting protein: VCY2IP-1, a microtubule-associated protein-like protein.
Microtubule-associated protein 1S, a short and ubiquitously expressed member of the microtubule-associated protein 1 family.
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MAP1S (C19ORF5) is the short, ubiquitously expressed MAP1 family member; it associates with stabilized microtubules, binds microtubules and tubulin, forms microtubule bundles, and (light chain) binds actin filaments.
Putative tumor suppressor RASSF1 interactive protein and cell death inducer C19ORF5 is a DNA binding protein.
Microtubule-associated protein 8 contains two microtubule binding sites.
Depletion of the Ras association domain family 1, isoform A-associated novel microtubule-associated protein, C19ORF5/MAP1S, causes mitotic abnormalities.
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MAP1S localizes to the centrosome/microtubule-organizing center and mitotic spindle; its depletion causes mitotic abnormalities (failure to form a stable metaphase plate, lagging chromosomes, multipolar spindles) and disrupts microtubule anchoring at the centrosome.
The NMDAR subunit NR3A interacts with microtubule-associated protein 1S in the brain.
EML3 is a nuclear microtubule-binding protein required for the correct alignment of chromosomes in metaphase.
The role of microtubule-associated protein 1S in SOCS3 regulation of IL-6 signaling.
Microtubule-associated protein 1S (MAP1S) bridges autophagic components with microtubules and mitochondria to affect autophagosomal biogenesis and degradation.
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MAP1S isoforms bind the autophagosome-associated LC3 (Atg8 homolog) and recruit it to stable microtubules, and bind the mitochondrion-associated protein LRPPRC (which links to the mitophagy initiator Parkin), integrating autophagic components with microtubules and mitochondria in autophagosome biogenesis and degradation. Map1s-knockout mice show accumulation of defective mitochondria and severe defects in the nutritive-stress response.
Nemitin, a novel Map8/Map1s interacting protein with Wd40 repeats.