Annotation inferences using phylogenetic trees

Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt

Gene Ontology annotation based on curation of immunofluorescence data

Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara

Combined Automated Annotation using Multiple IEA Methods

Pmel17 initiates premelanosome morphogenesis within multivesicular bodies.

Proteomic analysis of early melanosomes: identification of novel melanosomal proteins.

Epitope mapping of the melanosomal matrix protein gp100 (PMEL17): rapid processing in the endoplasmic reticulum and glycosylation in the early Golgi compartment.

MART-1 is required for the function of the melanosomal matrix protein PMEL17/GP100 and the maturation of melanosomes.

Proteomic and bioinformatic characterization of the biogenesis and function of melanosomes.

Premelanosome amyloid-like fibrils are composed of only golgi-processed forms of Pmel17 that have been proteolytically processed in endosomes.

Formation of Pmel17 amyloid is regulated by juxtamembrane metalloproteinase cleavage, and the resulting C-terminal fragment is a substrate for gamma-secretase.

The repeat domain of the melanosome fibril protein Pmel17 forms the amyloid core promoting melanin synthesis.

The pathogenic E. coli type III effector EspZ interacts with host CD98 and facilitates host cell prosurvival signalling.

BACE2 processes PMEL to form the melanosome amyloid matrix in pigment cells.

Apolipoprotein E Regulates Amyloid Formation within Endosomes of Pigment Cells.

Cloning and expression of the gene for the melanoma-associated ME20 antigen.

MITF-M-dependent PMEL gene expression

UniProt record for PMEL (P40967)