Gene Ontology annotation through association of InterPro records with GO terms
Annotation inferences using phylogenetic trees
Electronic Gene Ontology annotations created by ARBA machine learning models
Substrate specificity of the nonribosomal peptide synthetase PvdD from Pseudomonas aeruginosa.
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The purified first PvdD module activates L-threonine, but not D-threonine, L-serine or L-allo-threonine, in ATP-PPi exchange assays.
"showing that PvdD has peptide synthetase activity"
Characterization and genetic manipulation of peptide synthetases in Pseudomonas aeruginosa PAO1 in order to generate novel pyoverdines.
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A pvdD mutant makes no pyoverdine and lacks a high-Mr iron-regulated cytoplasmic protein; it is complemented in trans, and other pyoverdine NRPSs were identified.
"A pvdD mutant did not synthesize pyoverdine and lacked a high Mr iron-regulated cytoplasmic protein (IRCP)."
Quorum-sensing and siderophore biosynthesis in Pseudomonas aeruginosa: lasR/lasI mutants exhibit reduced pyoverdine biosynthesis.
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lasR and lasI mutants make less pyoverdine, but pvdD expression is unchanged in lasR mutants.
"lasR mutants were not altered with respect to expression of the pvdD gene involved in the synthesis of the peptide portion of pyoverdine"