ecm31 (Q09672, SPAC5H10.09c) notes

Role: ketopantoate hydroxymethyltransferase PanB (EC 2.1.2.11); module coenzyme_a_biosynthesis (pantoate branch, step 1).
Fetch: just fetch-gene SCHPO ecm31 FAILED (UniProt has no gene name for this entry: "PomBase; SPAC5H10.09c; -."); refetched with -u Q09672.

Evidence

• Family and reaction [UniProt:Q09672 "SIMILARITY: Belongs to the PanB family."]; no S. pombe experiments on activity.
• Mitochondrial in ORFeome screen PMID:16823372 (PomBase HDA). S. cerevisiae ECM31 deletion requires pantothenate PMID:19266201.
• Gene is adjacent to pan6 (SPAC5H10.08c).

Decisions

• cytoplasm IBA (seeded only by E. coli PanB) -> MODIFY to mitochondrion.
• monocarboxylic acid biosynthetic process -> MODIFY to pantothenate biosynthetic process.
• Mg binding IBA non-core.
• Core: GO:0003864 / GO:0015940 / GO:0005739 — matches S. cerevisiae ECM31 review and PomBase GO-CAM 67b1629100001098; YeastPathways places ECM31 in cytosol.