Annotation inferences using phylogenetic trees

Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt

Electronic Gene Ontology annotations created by transferring manual GO annotations between related proteins based on shared sequence features

Automatic assignment of GO terms using logical inference, based on on inter-ontology links

Electronic Gene Ontology annotations created by ARBA machine learning models

Lis1, the Drosophila homolog of a human lissencephaly disease gene, is required for germline cell division and oocyte differentiation.

Drosophila Lissencephaly-1 functions with Bic-D and dynein in oocyte determination and nuclear positioning.

Homologs of the alpha- and beta-subunits of mammalian brain platelet-activating factor acetylhydrolase Ib in the Drosophila melanogaster genome.

The Drosophila Lissencephaly1 (DLis1) gene is required for nuclear migration.

Drosophila Lis1 is required for neuroblast proliferation, dendritic elaboration and axonal transport.

Distinct mechanisms govern the localisation of Drosophila CLIP-190 to unattached kinetochores and microtubule plus-ends.

Live imaging of Drosophila brain neuroblasts reveals a role for Lis1/dynactin in spindle assembly and mitotic checkpoint control.

Dynein is required for polarized dendritic transport and uniform microtubule orientation in axons.

Spatial control of branching within dendritic arbors by dynein-dependent transport of Rab5-endosomes.

Dynein-dynactin complex is essential for dendritic restriction of TM1-containing Drosophila Dscam.

Lissencephaly-1 controls germline stem cell self-renewal through modulating bone morphogenetic protein signaling and niche adhesion.

Stress and muscular dystrophy: a genetic screen for dystroglycan and dystrophin interactors in Drosophila identifies cellular stress response components.

New dystrophin/dystroglycan interactors control neuron behavior in Drosophila eye.

Regulation of dynein localization and centrosome positioning by Lis-1 and asunder during Drosophila spermatogenesis.

Microtubules and Lis-1/NudE/dynein regulate invasive cell-on-cell migration in Drosophila.

Lissencephaly-1 promotes the recruitment of dynein and dynactin to transported mRNAs.

Drosophila CLIP-190 and mammalian CLIP-170 display reduced microtubule plus end association in the nervous system.

Efficient Endocytic Uptake and Maturation in Drosophila Oocytes Requires Dynamitin/p50.

Lissencephaly-1 dependent axonal retrograde transport of L1-type CAM Neuroglian in the adult drosophila central nervous system.

Falcon deep research report for Lis-1

UniProt entry Q7KNS3 (Lis-1, Drosophila melanogaster)

FlyBase gene description for Lis-1 (DROME)