Gene Ontology annotation through association of InterPro records with GO terms

Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity

Annotation inferences using phylogenetic trees

Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt

Automatic assignment of GO terms using logical inference, based on on inter-ontology links

Gene Ontology annotation of human sequence-specific DNA binding transcription factors (DbTFs) based on the TFClass database

Electronic Gene Ontology annotations created by ARBA machine learning models

Combined Automated Annotation using Multiple IEA Methods

Expression of MEF2 genes during human cardiac development.

Smad proteins function as co-modulators for MEF2 transcriptional regulatory proteins.

Cooperative activation of atrial naturetic peptide promoter by dHAND and MEF2C.

MEF2-dependent recruitment of the HAND1 transcription factor results in synergistic activation of target promoters.

The Notch coactivator, MAML1, functions as a novel coactivator for MEF2C-mediated transcription and is required for normal myogenesis.

Control of the SOST bone enhancer by PTH using MEF2 transcription factors.

MEF2C is activated by multiple mechanisms in a subset of T-acute lymphoblastic leukemia cell lines.

TGF-beta activates ERK5 in human renal epithelial cells.

An atlas of combinatorial transcriptional regulation in mouse and man.

A human MAP kinase interactome.

MicroRNA-21 dysregulates the expression of MEF2C in neurons in monkey and human SIV/HIV neurological disease.

Skeletal myosin light chain kinase regulates skeletal myogenesis by phosphorylation of MEF2C.

The MADS box transcription factor MEF2C regulates melanocyte development and is a direct transcriptional target and partner of SOX10.

The functional interactome landscape of the human histone deacetylase family.

MEF2C exon α: role in gene activation and differentiation.

MiR-135b-5p and MiR-499a-3p Promote Cell Proliferation and Migration in Atherosclerosis by Directly Targeting MEF2C.

Impact of cytosine methylation on DNA binding specificities of human transcription factors.

MiR-448 promotes vascular smooth muscle cell proliferation and migration in through directly targeting MEF2C.

Genetic interaction screen for severe neurodevelopmental disorders reveals a functional link between Ube3a and Mef2 in Drosophila melanogaster.

A reference map of the human binary protein interactome.

Using brain cell-type-specific protein interactomes to interpret neurodevelopmental genetic signals in schizophrenia.

hMEF2C gene encodes skeletal muscle- and brain-specific transcription factors.

Inhibition of myogenesis by transforming growth factor beta is density-dependent and related to the translocation of transcription factor MEF2 to the cytoplasm.

Myocyte enhancer factor 2C and Nkx2-5 up-regulate each other's expression and initiate cardiomyogenesis in P19 cells.

Regulation of the MEF2 family of transcription factors by p38.

Phosphorylation of MEF2 proteins by p38

Interaction of MyoD:E protein with MEF2

Control of mouse cardiac morphogenesis and myogenesis by transcription factor MEF2C.

Cooperative activation of muscle gene expression by MEF2 and myogenic bHLH proteins.

Activation of the transcription factor MEF2C by the MAP kinase p38 in inflammation.

MEF2C, a transcription factor that facilitates learning and memory by negative regulation of synapse numbers and function.

Transcription factor MEF2C influences neural stem/progenitor cell differentiation and maturation in vivo.

MEF2C transcription factor controls chondrocyte hypertrophy and bone development.

Mef2c is a direct transcriptional target of ISL1 and GATA factors in the anterior heart field during mouse embryonic development.

MEF2C haploinsufficiency caused by either microdeletion of the 5q14.3 region or mutation is responsible for severe mental retardation with stereotypic movements, epilepsy and/or cerebral malformations.

Regulation of skeletal myogenesis by association of the MEF2 transcription factor with class II histone deacetylases.

Cooperative interaction of Nkx2.5 and Mef2c transcription factors during heart development.

Physical interaction between TBX5 and MEF2C is required for early heart development.

Transcription factor Mef2c is required for B cell proliferation and survival after antigen receptor stimulation.

Mef2C is a lineage-restricted target of Scl/Tal1 and regulates megakaryopoiesis and B-cell homeostasis.

UniProtKB Q06413 entry for MEF2C