Gene Ontology annotation through association of InterPro records with GO terms
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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UniProt subcellular location mappings support nucleus, cytoplasm, endosome, plasma membrane, and plasmodesma annotations.
Electronic Gene Ontology annotations created by ARBA machine learning models
Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
The Arabidopsis BELL1 and KNOX TALE homeodomain proteins interact through a domain conserved between plants and animals.
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BEL1 and KNOX proteins form heterodimeric transcriptional complexes, and BEL1/STM coexpression suggests a meristem role.
"BEL1 and KNAT proteins can activate transcription only as a heterodimeric complex"
Regulation of CLV3 expression by two homeobox genes in Arabidopsis.
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STM contributes with WUS to CLV3 expression at later developmental stages.
"At later developmental stages, WUS promotes the level of CLV3 expression, together with STM"
The WUSCHEL and SHOOTMERISTEMLESS genes fulfil complementary roles in Arabidopsis shoot meristem regulation.
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STM suppresses differentiation and promotes cell division in the shoot meristem independently of WUS.
"STM suppresses differentiation independently of WUS and is required and sufficient to promote cell division"
The interaction of two homeobox genes, BREVIPEDICELLUS and PENNYWISE, regulates internode patterning in the Arabidopsis inflorescence.
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The paper supports BELL/KNOX protein interaction as a general mechanism, though it mainly studies BP and PNY.
"KNOX proteins interact with BEL1-like (BELL) homeodomain proteins"
VAAMANA--a BEL1-like homeodomain protein, interacts with KNOX proteins BP and STM and regulates inflorescence stem growth in Arabidopsis.
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VAAMANA/PNY interacts with STM and affects nuclear localization with KNOX partners.
"VAN interacts specifically with the class I KNOX proteins SHOOTMERISTEMLESS (STM), BREVIPEDICELLUS (BP), and KNAT6 (K6)"
A central role of Arabidopsis thaliana ovate family proteins in networking and subcellular localization of 3-aa loop extension homeodomain proteins.
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TALE homeodomain proteins form a dense interaction network, including KNOX-BELL interactions.
"supporting the notion that BELL/KNOX heterodimerization plays a general role in TALE protein function"
Arabidopsis KNOXI proteins activate cytokinin biosynthesis.
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STM/KNOXI activity induces AtIPT7, increases cytokinin levels, and cytokinin partially rescues stm mutants.
"activation of cytokinin biosynthesis mediates KNOXI function in meristem maintenance"
Nuclear import of the transcription factor SHOOT MERISTEMLESS depends on heterodimerization with BLH proteins expressed in discrete sub-domains of the shoot apical meristem of Arabidopsis thaliana.
The KNOX gene SHOOT MERISTEMLESS is required for the development of reproductive meristematic tissues in Arabidopsis.
Arabidopsis JACKDAW and MAGPIE zinc finger proteins delimit asymmetric cell division and stabilize tissue boundaries by restricting SHORT-ROOT action.
The Arabidopsis BEL1-LIKE HOMEODOMAIN proteins SAW1 and SAW2 act redundantly to regulate KNOX expression spatially in leaf margins.
MPB2C, a microtubule-associated protein, regulates non-cell-autonomy of the homeodomain protein KNOTTED1.
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AtMPB2C binds KN1/STM and regulates KNOX cell-to-cell trafficking through plasmodesmata.
"At MPB2C, are KN1/STM binding factors"
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The accessible source supports MPB2C RNA binding, not direct RNA binding by STM.
"Here, we show that MPB2C is an RNA and HD motif binding protein"
CrY2H-seq: a massively multiplexed assay for deep-coverage interactome mapping.
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CrY2H-seq is a high-throughput Arabidopsis TF interaction resource and is not sufficient by itself for generic STM protein-binding curation.
"uncovering a network of 8,577 interactions among 1,453 transcription factors"
FTIP-Dependent STM Trafficking Regulates Shoot Meristem Development in Arabidopsis.
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FTIP3/FTIP4 regulate STM localization, nuclear recycling, and intercellular trafficking in the shoot meristem.
"This facilitates STM recycling to the nucleus"
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Loss of FTIP3/4 increases STM plasma membrane localization and intercellular trafficking.
"STM localizes substantially to the plasma membrane, which promotes intercellular trafficking"
The KNOXI Transcription Factor SHOOT MERISTEMLESS Regulates Floral Fate in Arabidopsis.
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STM contributes to flower meristem identity through AP1/UFO-associated floral fate circuitry.
"This work suggests a genetic mechanism that underlies the activity of STM in the specification of flower meristem identity"
The protein-protein interaction landscape of transcription factors during gynoecium development in Arabidopsis.
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Broad gynoecium transcription-factor PPI mapping detected many interactions but does not provide STM-specific mechanistic support in the cached abstract.
"detected more than 250 protein-protein interactions"
UniProt record for Arabidopsis STM (Q38874)
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UniProt summarizes STM as a KNOX/TALE homeobox protein required for SAM formation and transcriptional regulation.
"Required for shoot apical meristem (SAM) formation during embryogenesis"
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UniProt summarizes STM subunits, protein partners, and regulated localization.
"May form heterodimeric complexes with TALE/BELL proteins BEL1, BLH2, BLH3, BLH8/PNF, BLH9/PNY and ATH1"
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UniProt lists dynamic localization through nucleus, plasmodesma, cytoplasm, endosome, cell membrane, and microtubule-associated cytosolic puncta.
"Dynamic localization via a plasmodesmata-mediated cell-to-cell transport"
Falcon deep research report for Arabidopsis STM
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Deep research synthesis identifies STM as a mobile TALE/KNOX homeodomain transcription factor that maintains the shoot apical meristem.
"STM (At1g62360; UniProt Q38874) encodes a mobile TALE/KNOX homeodomain transcription factor"
PANTHER PTHR11850 TALE homeobox family metadata
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PANTHER family context supports TALE homeobox DNA-binding transcription factor function, meristem/developmental roles, and heterodimeric complexes.
"The TALE homeobox family is characterized by a conserved DNA-binding homeodomain"