Gene Ontology annotation through association of InterPro records with GO terms

Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt

GO_REF:0000117

Electronic Gene Ontology annotations created by ARBA machine learning models

GO_REF:0000122

AtSubP analysis

PMID:10556049

Disruption of an RNA helicase/RNAse III gene in Arabidopsis causes unregulated cell division in floral meristems.

This source supports a DCL1/sus1 role in floral meristem cell proliferation/development, not cell plate formation mechanics.

PMID:12225663

CARPEL FACTORY, a Dicer homolog, and HEN1, a novel protein, act in microRNA metabolism in Arabidopsis thaliana.

PMID:15469823

Endogenous trans-acting siRNAs regulate the accumulation of Arabidopsis mRNAs.

PMID:15821876

Specific interactions between Dicer-like proteins and HYL1/DRB-family dsRNA-binding proteins in Arabidopsis thaliana.

This source supports DCL1 interaction with HYL1/DRB proteins, dsRNA binding, and nuclear localization in the plant miRNA-processing pathway.

PMID:15851028

microRNA-directed phasing during trans-acting siRNA biogenesis in plants.

PMID:16144699

MicroRNA biogenesis and function in plants.

PMID:16428603

The interaction between DCL1 and HYL1 is important for efficient and precise processing of pri-miRNA in plant microRNA biogenesis.

This source supports the DCL1-HYL1 interaction as important for efficient and precise pri-miRNA processing.

PMID:16699516

Dissecting Arabidopsis thaliana DICER function in small RNA processing, gene silencing and DNA methylation patterning.

PMID:17090584

Four plant Dicers mediate viral small RNA biogenesis and DNA virus induced silencing.

This source supports DCL1 production of CaMV leader-derived 21-nt siRNAs while identifying DCL4 as the major antiviral/VIGS Dicer.

PMID:17369351

Arabidopsis primary microRNA processing proteins HYL1 and DCL1 define a nuclear body distinct from the Cajal body.

PMID:17442570

Identification of nuclear dicing bodies containing proteins for microRNA biogenesis in living Arabidopsis plants.

This source supports nuclear D-bodies containing DCL1/HYL1 and related miRNA biogenesis proteins.

PMID:18003861

A novel class of bacteria-induced small RNAs in Arabidopsis.

PMID:18632581

The FHA domain proteins DAWDLE in Arabidopsis and SNIP1 in humans act in small RNA biogenesis.

PMID:21330492

MicroRNAs regulate the timing of embryo maturation in Arabidopsis.

PMID:24784759

Global Regulation of Embryonic Patterning in Arabidopsis by MicroRNAs.

PMID:26101256

Induced folding in RNA recognition by Arabidopsis thaliana DCL1.

This source supports induced folding and RNA recognition by Arabidopsis DCL1.

PMID:29982637

SMA1, a homolog of the splicing factor Prp28, has a multifaceted role in miRNA biogenesis in Arabidopsis.

PMID:8787738

SHORT INTEGUMENT (SIN1), a gene required for ovule development in Arabidopsis, also controls flowering time.

file:ARATH/DCL1/DCL1-deep-research-falcon.md

Falcon deep research for Arabidopsis DCL1

DCL1 is the nuclear RNase III enzyme of the Arabidopsis miRNA microprocessor, working with HYL1/DRB1 and SERRATE in D-bodies.

file:ARATH/DCL1/DCL1-uniprot.txt

UniProt record for Arabidopsis DCL1

UniProt describes DCL1 as an RNase III involved in PTGS and miRNA biogenesis by cleaving pri-miRNAs and pre-miRNAs.

file:interpro/panther/PTHR14950/PTHR14950-entries.csv

PANTHER PTHR14950 DICER-RELATED family entries

Arabidopsis DCL1 belongs to the DICER-RELATED family with other Dicer-like proteins; the family supports RNase III/Dicer function but not rRNA-processing transfer to DCL1.