GO_REF:0000002
Gene Ontology annotation through association of InterPro records with GO terms
GO_REF:0000033
Annotation inferences using phylogenetic trees
GO_REF:0000044
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
GO_REF:0000052
Gene Ontology annotation based on curation of immunofluorescence data
PMID:20613862
A genome-scale DNA repair RNAi screen identifies SPG48 as a novel gene associated with hereditary spastic paraplegia.
PMID:22022230
The fifth adaptor protein complex.
PMID:23825025
Interaction between AP-5 and the hereditary spastic paraplegia proteins SPG11 and SPG15.
PMID:26085577
Loss of AP-5 results in accumulation of aberrant endolysosomes: defining a new type of lysosomal storage disease.
PMID:29381698
Role of the AP-5 adaptor protein complex in late endosome-to-Golgi retrieval.
PMID:33464297
Rag GTPases and phosphatidylinositol 3-phosphate mediate recruitment of the AP-5/SPG11/SPG15 complex.
PMID:40175557
Structural basis for membrane remodeling by the AP5-SPG11-SPG15 complex.
PMID:40081374
Bi-allelic variants in three genes encoding distinct subunits of the vesicular AP-5 complex cause hereditary macular dystrophy.
PMID:19140243
A structural explanation for the binding of endocytic dileucine motifs by the AP2 complex.
PMID:23222959
Mutations in AP2S1 cause familial hypocalciuric hypercalcemia type 3.
file:human/AP5S1/AP5S1-bioinformatics/RESULTS.md
AP5S1 (sigma-5): what the AP-5 structure says the subunit does
file:human/AP5S1/AP5S1-uniprot.txt
UniProtKB entry Q9NUS5 (AP5S1_HUMAN)
file:human/AP5S1/AP5S1-deep-research-affinage.md
Affinage mechanistic annotation for AP5S1 (human)